康复新联合埃索美拉唑治疗消化性溃疡疗效分析

目的研究康复新联合埃索美拉唑治疗消化性溃疡的疗效。方法230例经胃镜检查确诊为消化性溃疡的患者随机分为两组，每组115例。治疗组口服康复新液10mL，每日3次；埃索美拉唑40mg，每日1次。对照组口服埃索美拉唑40mg，每日1次，两组疗程均为4周。治疗结束后观察症状改善情况，并评价胃镜下溃疡愈合情况。结果经过4周的治疗两组患者症状评分显著低于治疗前（P〈0．01），其中治疗组上腹痛和上腹饱胀改善与对照组比较，差异有统计学意义，其他症状虽优于对照组，但差异无统计学意义；胃镜评分显示治疗组总有效率为99．13％，对照组为98．26％，虽显著优于治疗前，但两组间比较差异无统计学意义。结论康复新联合埃索美拉唑治疗消化性溃疡更加有效改善症状。

Efficacy Analysis of Peptic Ulcer Treated with Kangfuxin and Esomeprazole

Objective To study the efficacy on peptic ulcer treated with the combined medication of kangfuxin and esopeprazole. Methods Two hundred and thirty cases of peptic ulcer diagnosed with gastroscopy and treated in the hospital were randomized into two groups, 115 cases in each one. In the treatment group,the combined medication of kangfuxin liquid 10 mL three times a day and esopeprazole,40 mg, once per day was prescribed. In the control group, esopeprazole was prescribed for oral administration,40 mg, once per day. The course of treatment was 4 weeks in two groups. At the end of treatment, the improvements in symptoms were observed and ulcer healing was evaluated under gastroscope. Results After 4 weeks treat- ment, the symptom score was lower significantly as compared with that before treatment in either group （ P 〈 0.01 ） ,in which, the improvements in epigastrie pain and distention in the treatment group were different sig- nificantly as compared with the control group;and those in the other symptoms were superior to the control group, but without significant difference in statistics. The gastroscope score indicated that the total effective rate was 99.13% in the treatment group and was 98.26% in the control group. Although the significance was superior to that before treatment, the difference was not significant statistically in comparison between two groups. Conclusion The combined medication of kangfuxin and esomeprazole improves much more effectively in the symptoms of peptic ulcer.