椎-基底动脉重度狭窄的血管内治疗

目的回顾性分析椎-基底动脉重度狭窄患者临床诊断与治疗经过,以评价血管内支架成形术的可行性和临床疗效。方法16例椎-基底动脉重度狭窄患者均施行血管内支架成形术,观察其技术成功率、围手术期并发症发生率及远期疗效。结果16例患者经脑血管造影检查共发现27个狭窄病变,共成功植入36枚球囊扩张式支架,技术成功率达100%(16/16)。1例于手术后24h发生支架内急性血栓形成,围手术期并发症发生率为6.25%(1/16)。随访期间,3例(18.75%)发生支架内再狭窄而致卒中再发。结论血管内支架成形术治疗椎-基底动脉重度狭窄,在技术上可行,远期疗效良好。

Endovascular treatment of severe vertebrobasilar artery stenosis

Objective To retrospectively analyse the clinical diagnosis and treatment of patients with severe vertebrobasilar artery stenosis and to evaluate the feasibility and clinical effectiveness of stent-assisted angioplasty.Methods Sixteen patients with severe vertebrobasilar artery stenosis were treated by stent-as-sisted angioplasty.Technical success rate,perioperative complication rate and long-term follow-up result were evaluated.Results In 16 patients 27 stenotic lesions were found by cerebral angiography.A total of 36 balloon-mounted stents were successfully implanted.The technical success rate was 100%(16 / 16).After 24 h-operation,one patient occurred in-stent aucte thrombosis,the perioperative complication rate was 6.25%(1 / 16).During the follow-up period,3 patients(18.75%) had recurrence of stroke due to in-stent restenosis con-firmed by cerebral angiography or transcranial Doppler(TCD).Conclusion Stent-assisted angioplasty is a feasible technical method for the treatment of severe vertebrobasilar artery stenosis,and the long-term effect is good.