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两株小鼠肝癌细胞增殖状态比较研究
引用本文:张晨,董瑞琪,侯力,白洁,凌茂英. 两株小鼠肝癌细胞增殖状态比较研究[J]. 大连医科大学学报, 2000, 22(3): 180-181
作者姓名:张晨  董瑞琪  侯力  白洁  凌茂英
作者单位:1. 解放军第210医院中医血液病研究所,辽宁,大连,116021
2. 大连陆军学院,辽宁,大连,116100
3. 大连医科大学病理学教研室,辽宁,大连,116027
摘    要:目的:探讨细胞增殖状态与细胞转移力的关系。方法:采用流式细胞术,测定两株腹水型肝癌细胞的DNA含量,进而提供细胞增殖状态的信息。结果:F和P细胞的DNA指数及细胞增殖指数均无显著性差异。F细胞的淋巴结转移瘤的G2/M期比率高于其原发瘤。结论:两株细胞的转移率与细胞的增殖状态无明显的相关性。

关 键 词:肝癌 细胞增殖状态 流式细胞术 细胞周期
文章编号:1000-5676 (2000) 03-0180-02
修稿时间:2000-04-17

The comparison between two hepatic tumor cell lines with different metastatic capacity on cell distribution
ZHANG Chen,DONG Rui-qi,HOU Li. The comparison between two hepatic tumor cell lines with different metastatic capacity on cell distribution[J]. Journal of Dalian Medical University, 2000, 22(3): 180-181
Authors:ZHANG Chen  DONG Rui-qi  HOU Li
Affiliation:ZHANG Chen,DONG Rui-qi,HOU Li(Hematology Institute of Traditional Chinese Medicine,The 210th Hospital,Dalian 116021 China)
Abstract:Objective:To investigate the relationship of cell cycle distribution and metastasis in two tumor cell lines.Methods:The DNA contents of two hepatic carcinoma cell lines were studied by flow cytometry.Results:The DNA index and proliferative index between higher metastatic F cell and lower metastatic P cell were no significant differences,but G 2/M phase of tumor cells with lymphatic metastasis were remarkably higher than that of F cell in non-metastasis.Conclusion:The two hepatic carcinoma cell lines with different lymph node metastatic capacities were no differences in cell proliferation.
Keywords:flow cytometry  cell Lines  cell cycle distribution
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