| 兔后肢急性缺血与伴行静脉血栓形成关系的实验研究 |
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| 引用本文： | 刘国龙,杨牟,张居文,曹小丽,吴隆敬.兔后肢急性缺血与伴行静脉血栓形成关系的实验研究[J].青岛大学医学院学报,2008,44(3):254-255. |
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| 作者姓名： | 刘国龙 杨牟 张居文 曹小丽 吴隆敬 |
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| 作者单位： | 1. 青岛大学医学院,山东,青岛,266021
2. 青岛大学附属烟台毓璜顶医院 |
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| 摘 要： | 目的 通过制作兔后肢急性缺血模型,观察股动脉结扎对股静脉血流速度及血液流变学指标的影响,以及是否有形成静脉血栓的倾向.方法 将20只成年健康大白兔随机分为对照组(A组)和实验组(B组),每组 10只.B组结扎右后肢股动脉,制作肢体急性缺血模型,A组处理方法同B组,只是不结扎股动脉.测定术前及术后20 min、24 h、48 h及72 h股静脉血流速度;测定术前及术后24 h、48 h和72 h的全血黏度、血浆黏度和红细胞聚集指数.结果 A组术前与术后股静脉血流速度比较差异无显著性(P>0.05),B组术后20 min、24 h、48 h及72 h股静脉血流速度较术前明显降低(F=209,q=31.55～32.82,P<0.01);B组术后24 h、48 h及72 h血黏度较术前增高,而A组无差别.B组有4只动物伴行静脉内有血栓形成,A组动物无静脉血栓形成.结论 结扎兔股动脉后,股静脉血流速度明显减慢,血黏度增高,预示有形成静脉血栓的倾向.
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| 关 键 词： | 四肢 缺血 血流速度 血黏度 血栓形成 兔 |
| 文章编号： | 1672-4488(2008)03-0254-03 |
| 修稿时间： | 2007年1月8日 |
THE RELATIONSHIP BETWEEN ACUTE ISCHEMIC HIND LIMB AND ACCOMPANYING VEIN THROMBOSIS:AN EXPERIMENTAL STUDY IN RABBITS |
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| LIU GUO-LONG,YANG MU,ZHANG JU-WEN,et al.THE RELATIONSHIP BETWEEN ACUTE ISCHEMIC HIND LIMB AND ACCOMPANYING VEIN THROMBOSIS:AN EXPERIMENTAL STUDY IN RABBITS[J].Acta Academiae Medicinae Qingdao Universitatis,2008,44(3):254-255. |
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| Authors: | LIU GUO-LONG YANG MU ZHANG JU-WEN |
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| Institution: | LIU GUO-LONG,YANG MU,ZHANG JU-WEN,et al(Qingdao University Medical College,Qingdao 266021,China) |
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| Abstract: | Objective To study the changes of femoral vein blood flow velocity and hemorheology by establishing an experimental rabbit model of acute hind limb ischemia,and observe if there is a thrombotic tendency. Methods Twenty healthy rabbits were evenly divided into two groups: normal control group(A) and experimental group(B).An ischemia model was made by ligating the right femoral artery in rabbits of group B,while the rabbits in group A were treated with the same as group B,apart from ligature of the artery.The... |
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| Keywords: | Extrimities Ischemia Blood flow velocity Thrombosis Rabbits |
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