| 猪苓多糖抗衰老作用的实验研究 |
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| 引用本文： | 张英华 秦腊梅. 猪苓多糖抗衰老作用的实验研究[J]. 中药新药与临床药理, 1993, 4(2): 15-18 |
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| 作者姓名： | 张英华 秦腊梅 |
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| 作者单位： | 中国中医研究院中药所，中国中医研究院中药所，中国中医研究院中药所，北京中医学院附属东直门医院，北京中医学院附属东直门医院，北京中医学院附属东直门医院 北京 100700，北京 100700，北京 100700，北京 100700，北京 100700，北京 100700 |
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| 摘 要： | 报道猪苓多糖对衰老模型小鼠的几个重要的抗衰老指标药理作用的研究。结果表明,猪苓多糖能增加衰老模型小鼠体重,提高体温和胸腺系数,使其接近正常。猪苓多糖还能降低衰老模型小鼠肝中过氧化脂质的含量,提高衰老模型小鼠红细胞中超氧化物歧化酶和肝脏过氧化氢酶活力。
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| 关 键 词： | 猪苓/药理学 @猪芩多糖注射液/药理学 过氧化脂质类/代谢 过氧化氢酶类/代谢 肝/酶学 超氧化物歧化酶类/血液 血红蛋白/酶学 衰老/药物作用 动物 小鼠 |
Experimental Study on the Anti-aging Effect of Polyporus Umbellatus Polysaccharide |
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| Zhang Yinghua Qin Lamei Zhang Kuihan. Experimental Study on the Anti-aging Effect of Polyporus Umbellatus Polysaccharide[J]. Traditional Chinese Drug Research & Clinical Pharmacology, 1993, 4(2): 15-18 |
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| Authors: | Zhang Yinghua Qin Lamei Zhang Kuihan |
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| Abstract: | Polyporus Umbellatus polysaccharide(PUP) is a new medicine made by our institute. A model of aged mice was prepared by placing 2-month mice in an ozone circumstance (O_3 conoentration 1. 298 ppm) for 10 days. After the aged mice was fed with PUP for 10 days, the average body weight, body temperature and thymus coefficient can be increased to normal level, superoxide dismutase (SOD) activity of red cells and catalase activity of liver were increased, and liver lipoperoxide (LOP) reduced. It is suggested that PUP may be a good anti-aging agent. |
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| Keywords: | POLYPORUS UMBELLATUS/pharmacology @ POLYPORUS UMBELLATUS POLYSACCHARIDE/pharmacology LIPID PEROXIDES/metabohsm LIVER/enzymology SUPEROXIDE DISMUTASE/blood HEMOGLOBIN/enzymology AGING/drug effects ANIMAL MICE |
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