妊高征患者围产期脐动脉血流与胎盘病理学改变的相关性研究

目的:探讨妊高征患者脐动脉血流改变与子宫胎盘病理学变化的相关性,从而预测妊娠结局。方法:观察记录72例妊高征患者的脐动脉血流参数S/D值、搏动指数(PI)、阻力指数(R I)及胎盘形态变化,分析血流参数与病理评分的相关性。结果:随着S/D值、搏动指数和阻力指数的增高,妊高征患者的胎盘重量减轻,呈现逐渐加重的病理改变。结论:妊高征患者脐动脉血流改变与胎盘形态学病理变化存在明显的相关性,可通过脐动脉多普勒超声的血流改变来判断胎盘病理变化。

Relationship between cord aretery blood flow and pathological characteristics of placenta in pregnancy induced hypertension

Objective:To study the realationship between cord artery blood flow and morphological characteristics of placenta in pregnancy induced hypertension(PIH) and to evaluate further clinical advantages of cord blood flow change in forecasting pregnant outcome.Methods:72 PIH patients who had their deliveries in the hospital 2002~2004 suffered from some examinations such as S/D ratio、PI、RI、were calculated by color Doppler flow imaging.Placental specimen morphological changes observed by light microscopy.Results:Gradually,weight of placenta decreases and pathological goes worse in PIH with S/D,PI and RI increasing.Conclusion:The changes of cord artery blood flow has a close relationship with morphological characteristics of placenta in PIH(positive correlation).We can speculate about pathology fo placenta by color Doppler folw imaging.