| 蛇毒抗肿瘤成分的研究进展 |
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| 引用本文： | 赵健楠,孙晋民. 蛇毒抗肿瘤成分的研究进展[J]. 西北药学杂志, 2017, 0(3): 391-393. DOI: 10.3969/j.issn.1004-2407.2017.03.039 |
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| 作者姓名： | 赵健楠 孙晋民 |
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| 作者单位： | 1. 中国医科大学,沈阳,110013;2. 中国医科大学科学实验中心,沈阳,110013 |
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| 基金项目： | 辽宁省科技基金项目(2008225021-1)，辽宁省科技基金项目(2013225021)，专利:国家知识产权局发明专利第476108号 |
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| 摘 要： | 目的探讨蛇毒抗肿瘤成分的作用及其在医药领域的应用,为蛇毒成分在抗肿瘤领域的研发提供参考。方法查阅并总结资料文献,对国内外蛇毒抗肿瘤成分的研究进行综述。结果蛇毒具有多种抗肿瘤成分,对多种肿瘤均有抑制作用,可抑制肿瘤相关的基因表达、抑制肿瘤细胞增殖、诱导肿瘤细胞凋亡和抑制肿瘤血管再生与转移等。结论对蛇毒抗肿瘤成分进行深入研究,开发其在抗肿瘤药物研究领域的价值。
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| 关 键 词： | 蛇毒 抗肿瘤 抗肿瘤成分 |
The progress of the anti-tumor components of snake venom |
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| ZHAO Jiannan,SUN Jinmin. The progress of the anti-tumor components of snake venom[J]. Northwest Pharmaceutical Journal, 2017, 0(3): 391-393. DOI: 10.3969/j.issn.1004-2407.2017.03.039 |
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| Authors: | ZHAO Jiannan SUN Jinmin |
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| Abstract: | Objective To explore the application of the anti-tumor components of snake venom in the field of medicine and to provide a reference for research of the components of snake venom in the field of anti-tumor.Methods The literature of research and review of the anti-tumor components of snake venom both at domestic and abroad were summarized.Results Snake venom contained a variety of anti-tumor components by inhibiting the expression of tumor-related gene,the proliferation of tumor cell,tumor angiogenesis and inducing the apoptosis of tumor cell.Conclusion Study of the anti-tumor components of snake venom in depth has great value in the field of anti-tumor drugs research. |
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| Keywords: | snake venom anti-tumor anti-tumor component |
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