| 新生儿高胆红素血症心肌肌钙蛋白T的变化 |
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| 引用本文： | 常彩红,牛德亮. 新生儿高胆红素血症心肌肌钙蛋白T的变化[J]. 中国妇幼保健, 2006, 21(17): 2367-2368 |
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| 作者姓名： | 常彩红 牛德亮 |
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| 作者单位： | 1. 郑州大学第三附属医院检验科,450052
2. 河南中医学院第一附属医院检验科 |
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| 摘 要： | 目的:探讨新生儿高胆红素血症时心肌肌钙蛋白T(cTnT)的变化及其临床意义。方法:采用化学免疫系统和全自动生化分析仪,对38例高胆红素血症患儿血清cTnT及IBIL进行检测,同时选20例生理性黄疸新生儿作为对照。结果:各组新生儿血清中cTnT水平:重度高胆红素血症组显著高于轻度组(P<0·01)和对照组(P<0·01),轻度组与对照组无显著性差异(P>0·05)。结论:新生儿高胆红素血症可以引起心肌的损害,血清cTnT水平升高程度与IBIL成正相关。cTnT的检测可以为临床治疗提供实验依据。
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| 关 键 词： | 新生儿 高胆红素血症 肌钙蛋白T 心肌损伤 |
| 文章编号： | 1001-4411（2006）17-2367-02 |
| 修稿时间： | 2005-07-02 |
The variety of cardial troponin T in neonates with hyperbilimbinemia |
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| CHANG Cai-Hong,NIU De-Liang. The variety of cardial troponin T in neonates with hyperbilimbinemia[J]. Maternal and Child Health Care of China, 2006, 21(17): 2367-2368 |
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| Authors: | CHANG Cai-Hong NIU De-Liang |
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| Affiliation: | Test Department of The Third Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, Henan, China; Test Department of The First Affiliated Hospital of Henan Traditional Chinese Medicine, Zhengzhou 450000, Henan, China |
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| Abstract: | Objective:To detect the variety and the clinical value of cardial troponin T in neonates with hyperbilirubinemia.Methods:The levels of cTnT and IBIL were measured by full-automatic chemo-immune system and biochemistry system in 38 neonates with hyperbilirubinemia and 20 physio-bilirubinemia nenates as control.Results:The levels of cTnT in serum: increased obviously in severe hyperbilirubinemia group than those of in mild hyperbilimbinemia (P<0.01) group and control (P<0.01), there was no significant difference between mild hyperbilirubinemia and control (P>0.05).Conclusion:The level of cTnT increase greatly as the result of hyperbilirubinemia-induced myocardial damage. The concentrations of serum cTnT and IBIL have notable positive correlation. Monitoring the level of cTnT in serum might provide an index for clinic. |
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| Keywords: | Neonate Hyperbilirubinemia Cardiac troponinT (cTnT) Myocardial damage |
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