脐血和不同年龄组成人红细胞聚集、变形能力的分析

目前国内对心、脑血管等疾病的红细胞流变学研究较多，而对新生儿脐血的红细胞聚集、变形尚未见报道。我们测定了２０例足月新生儿脐带血和１１５例不同年龄健康成人的红细胞聚集、变形指数，并进行比较分析，以探讨新生儿红细胞聚集、变形能力的特点及增龄对成人红细胞流变性的影响。１　资料和方法１．１　对象脐血组：足月健康新生儿２０例，男性９例、女性１１例；成人组：健康成人１１５例，男性５４例、女性６１例，按不同年龄分组，１组１８～２９岁，２组３０～３９岁，３组４０～４９岁，４组５０～５９岁，５组＞６０岁。经体检均…

Analysis on Erythrocyte Aggregation and Deformation in Cord Blood and Different Age of Adult

Objective: To explore the specialties of erythrocyte aggregation and deformation in newborns, the effect of age increase on erythrocyte rheology of health adult. Methods: The level of erythrocyte aggregation(Optical density assay) and deformation(Laser diffraction assay) were measured in 20 cases of cord blood, 115 cases of different age healthy adult. Results: The erythrocyte aggregation in cord blood group( 7.76 ± 0.80 ) were higher( P < 0.05 ) than those in middle age and youth control( 6.85 ± 0.82 , 6.77 ± 0.81 ). Erythrocyte aggregation and deformation in between other groups can be compared no significance. Conclusion: Newborns have good ability of erythrocyte aggregation and deformation; The age increase has no marked influence on erythrocyte aggregation and deformation of health adults. The study is conducive to distinguish abnormal and pathologic erythrocyte rheology in clinic.