| HBV感染与原发性肝癌关系的探讨 |
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| 引用本文： | 李长林,李秋梅,姜宝法,冯月秋,李笠. HBV感染与原发性肝癌关系的探讨[J]. 山东大学学报(医学版), 1989, 0(3) |
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| 作者姓名： | 李长林 李秋梅 姜宝法 冯月秋 李笠 |
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| 作者单位： | 山东医科大学流行病学教研室(李长林，姜宝法，冯月秋)，山东医科大学传染病学教研室(李秋梅)，山东医科大学流行病学教研室(李笠) |
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| 摘 要： | 采用配比的方法,以原发性肝癌、肝硬化、慢性乙型肝炎和非肝病病人为研究对象,检测其HBV感染6项血清学标志。结果表明,原发性肝癌、肝硬化、慢性肝炎的HBV感染总阳性率分别为98.21%,93.75%和96.43%;与对照组有显著差异;3组的感染标志组合较一致,HBsAg和抗-HBc双阳性为主;HBeAg在肝硬化和慢性肝炎中明显高于肝癌组;抗-HBe和抗-HBcIgM3组间无显著差别。提示HBV感染的慢性化与原发性肝癌病因有密切联系。
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| 关 键 词： | 乙型肝炎病毒 肝肿瘤 肝硬变 乙型肝炎 血清学标志 |
THE RELATIONSHIP BETWEEN HEPATITIS B VIRUS INFECTION AND PRIMARY HEPATOCELLULAR CARCINOMA |
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| Li Changlin,et al Dept.of Epidemiology,Shandong Medical University. THE RELATIONSHIP BETWEEN HEPATITIS B VIRUS INFECTION AND PRIMARY HEPATOCELLULAR CARCINOMA[J]. Journal of Shandong University:Health Sciences, 1989, 0(3) |
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| Authors: | Li Changlin et al Dept.of Epidemiology Shandong Medical University |
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| Abstract: | In an attempt to clarify the relationship between HBV in-fection and hepatocellular carcinoma,we have studied the HBV infectionserum marks in 448 patients suffering from hepatocellular carcinoma(PHC),chronic hepatitis B(CHB),liver cirrhosis(LC)and non-liver di-seases(NLD).The incidence of HBV infection serum marks were res-pectively 98.21% in PHC,96.43% in CHB and 93.75% in LC,signifi-cantly higher than that in controls,The major combination of serum markswas HBsAg and anti-HBC among liver disease patients,The incidencefor anti-HBe and anti-HBcIgM were no significant difference amongthe three liver disease groups,but HBeAg was significantly higher inCHB and in LC.The result indicated HBV infection was closely associ-ated with PHC. |
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| Keywords: | Hepatitis B virus Liver neoplasms Liver cirrhosis Hepatitis B Serum Marks |
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