| AN ENZYMOCYTOCHEMICAL STUDY OF ALKALINE PHOSPHATASE ISOENZYMES IN GASTRIC CANCER－LIGHT AND ELECTRON |
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| 引用本文： | 苏英豪,杨光霖,董聿明,张红,吴继锋,王道斌. AN ENZYMOCYTOCHEMICAL STUDY OF ALKALINE PHOSPHATASE ISOENZYMES IN GASTRIC CANCER－LIGHT AND ELECTRON[J]. 中国癌症研究, 1995, 7(2): 141-147. DOI: 10.1007/BF03014412 |
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| 作者姓名： | 苏英豪 杨光霖 董聿明 张红 吴继锋 王道斌 |
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| 作者单位： | Department of Pathology，Anhui Medical University，Hefei 230032 |
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| 摘 要： | ＡＮＥＮＺＹＭＯＣＹＴＯＣＨＥＭＩＣＡＬＳＴＵＤＹＯＦＡＬＫＡＬＩＮＥＰＨＯＳＰＨＡＴＡＳＥＩＳＯＥＮＺＹＭＥＳＩＮＧＡＳＴＲＩＣＣＡＮＣＥＲ－ＬＩＧＨＴ ＡＮＤＥＬＥＣＴＲＯＮＭＩＣＲＯＳＣＯＰＩＣＯＢＳＥＲＶＡＴＩＯＮＳＳｕＹｉｎｇｈａｏ苏英豪；...
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An enzymocytochemical study of alkaline phos-phatase isoenzymes in gastric cancer — Light and electron microscopic observations |
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| Yinghao Su,Guanglin Yang,Yuming Dong,Hong Zhang,Jifeng Wu,Daobin Wang. An enzymocytochemical study of alkaline phos-phatase isoenzymes in gastric cancer — Light and electron microscopic observations[J]. Chinese Journal of Cancer Research, 1995, 7(2): 141-147. DOI: 10.1007/BF03014412 |
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| Authors: | Yinghao Su Guanglin Yang Yuming Dong Hong Zhang Jifeng Wu Daobin Wang |
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| Affiliation: | 1. Department of Pathology, Anhui Medical University, 230032, Hefei
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| Abstract: | By using light and electron microscopic cytochemical technique, the activities and distributions of AP isoenzymes in gastric cancers and benign gastric diseases were examined.The results showed: Nagao, Regan and Kasahara isoenzymes, which were not expressed in normal gastric mucosae and non-malignant lesions, might be considered as tumor markers of gastric cancer;The epithelium of intestinal metaplasia exhibited intestinal-type AP only,which was one of the markers of well-differentiated intestinal metaplasia.In the view-point of the gene expression of AP isoenzymes, two mutation hypothesis and recessive-gene mutation hypothesis might be fit for gastric cancer. |
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| Keywords: | Alkaline phospbatase isoenzymes Gastric cancer Cytochemistry Light microscopy Electron microscopy. |
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