| 穿地龙对角叉菜胶所致小鼠足跖肿胀抗炎肿作用的观察 |
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| 引用本文： | 庞晓东,林耀庚,李宝丽,唐方. 穿地龙对角叉菜胶所致小鼠足跖肿胀抗炎肿作用的观察[J]. 天津中医药, 2002, 19(5): 44-45 |
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| 作者姓名： | 庞晓东 林耀庚 李宝丽 唐方 |
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| 作者单位： | 天津医科大学总医院,天津,300052 |
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| 基金项目： | 天津市卫生局资助课题(200032) |
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| 摘 要： | 目的探讨穿地龙在关节炎中抗炎作用的效果.方法采用角叉菜致小鼠足水肿的急性非感染炎症模型,设立模型组、普威对照组,用不同剂量穿地龙水煎剂于造模前3 d给小鼠灌胃,1次/d,千分尺测量造模前及造模后2、4、6、8、24 h足跖垫厚度及检测24 h血清唾液酸水平.结果穿地龙可明显减轻模型8、24 h小鼠足肿胀(P＜0.05),对小鼠血清唾液酸水平没有影响.结论提示穿地龙在这种急性炎症模型中有抗急性炎症作用.
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| 关 键 词： | 穿地龙 小鼠 炎症 足跖肿胀 |
| 文章编号： | 1004-5392(2002)05-0044-02 |
| 收稿时间： | 2002-05-20 |
| 修稿时间： | 2002-05-20 |
Observation of Anti-inflammation of Chuandilong''''s in Carrageenin- induced in Mouse Metatarsus |
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| Pang Xiaodong,Lin Yaogeng,Li Baoli. Observation of Anti-inflammation of Chuandilong''''s in Carrageenin- induced in Mouse Metatarsus[J]. Tianjin Journal of Traditional Chin Medicine, 2002, 19(5): 44-45 |
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| Authors: | Pang Xiaodong Lin Yaogeng Li Baoli |
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| Affiliation: | The General Hospital to Tianjin Medical University, Tianjin 300052, China;The General Hospital to Tianjin Medical University, Tianjin 300052, China;The General Hospital to Tianjin Medical University, Tianjin 300052, China;The General Hospital to Tianjin Medical University, Tianjin 300052, China |
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| Abstract: | Objective: To study the anti-inflammatory effect of Chuandilong (dioscorea nipponica) on arthritis. Methods: The model of acute non-infectious inflammation was induced by carrageenin. There were 2 groups: model group and control group (given Nimesulide).Chuandilong with different dosage, once a day, was given to all mice 3 days before the models were made. The thickness of metatarsus was measured before and 2, 4, 6, 8, 24 hours after the models were made. And serum salivary sialic acid was tested 24 hours after that.Results: Chuandilong could improve the swelling at 8, 24 hours obviously (P<0.05), and has no effect on serum sialic acid. Conclusion: Chuandilong has an anti-inflammatory effect on this mode. |
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| Keywords: | Chuandilong mouse inflammation metatarsal swelling |
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