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A tiny esophageal cancer diagnosed accurately by magnifying endoscopy and endocytoscopy: report of a case
Authors:Youichi Kumagai  Kaiyo Takubo  Michio Iida  Shigeru Yamazaki  Tatsuyuki Kawano
Affiliation:(1) Department of Surgery, Ohta Nishinouchi Hospital, 2-5-20 Nishinouchi, Kohriyama 963-8558, Japan;(2) Research Team for Geriatric Diseases (Human Tissue Research Group), Tokyo Metropolitan Institute of Gerontology, Tokyo, Japan;(3) Department of Surgery, Tokyo Medical and Dental University, Tokyo, Japan
Abstract:An 82-year-old woman presented for a periodic endoscopic examination after radiotherapy and endoscopic mucosal resection (EMR) of a cancer in the esophagus. Conventional endoscopy demonstrated a tiny, flat, reddish lesion about 1 mm in diameter proximal to the scar of the previous esophageal EMR. Observation after iodine staining showed an apparent unstained area in the lesion. Magnifying observation using a Q240Z (Olympus, Tokyo, Japan) revealed a clearly demarcated aggregation of dilated intrapapillary capillary loops in this part of the lesion. Endocytoscopic observation (XEC120U prototype; Olympus) showed increased cellular density and irregularity of the epithelial nuclei. Endoscopic mucosal resection of the lesion was performed. Pathological studies of the resected specimen revealed a squamous cell carcinoma, maximal diameter 920 μm, confined to the epithelium. We believe that the Endocytoscope has the potential to reduce biopsy histology in cases of esophageal squamous cell carcinoma.
Keywords:Esophageal cancer  Magnifying endoscopy  Endocytoscopy system  Endoscopic mucosal resection
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