A tiny esophageal cancer diagnosed accurately by magnifying endoscopy and endocytoscopy: report of a case |
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Authors: | Youichi Kumagai Kaiyo Takubo Michio Iida Shigeru Yamazaki Tatsuyuki Kawano |
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Affiliation: | (1) Department of Surgery, Ohta Nishinouchi Hospital, 2-5-20 Nishinouchi, Kohriyama 963-8558, Japan;(2) Research Team for Geriatric Diseases (Human Tissue Research Group), Tokyo Metropolitan Institute of Gerontology, Tokyo, Japan;(3) Department of Surgery, Tokyo Medical and Dental University, Tokyo, Japan |
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Abstract: | An 82-year-old woman presented for a periodic endoscopic examination after radiotherapy and endoscopic mucosal resection (EMR) of a cancer in the esophagus. Conventional endoscopy demonstrated a tiny, flat, reddish lesion about 1 mm in diameter proximal to the scar of the previous esophageal EMR. Observation after iodine staining showed an apparent unstained area in the lesion. Magnifying observation using a Q240Z (Olympus, Tokyo, Japan) revealed a clearly demarcated aggregation of dilated intrapapillary capillary loops in this part of the lesion. Endocytoscopic observation (XEC120U prototype; Olympus) showed increased cellular density and irregularity of the epithelial nuclei. Endoscopic mucosal resection of the lesion was performed. Pathological studies of the resected specimen revealed a squamous cell carcinoma, maximal diameter 920 μm, confined to the epithelium. We believe that the Endocytoscope has the potential to reduce biopsy histology in cases of esophageal squamous cell carcinoma. |
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Keywords: | Esophageal cancer Magnifying endoscopy Endocytoscopy system Endoscopic mucosal resection |
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