男性乳腺癌临床研究进展

男性乳腺癌高峰年龄为50~60岁,发病主要与内分泌异常、遗传、损伤等因素有关,内源性激素可能起主要作用。首发症状以乳晕下及周围无痛性肿块为最常见,早期易侵犯胸肌及区域淋巴结,病理类型以浸润性导管癌最常见。受体阳性率高,腋窝淋巴结转移情况是最重要的预后指标,手术为首选治疗方法,辅以放化疗,受体阳性者加用激素治疗,晚期病例首选切除双侧睾丸治疗。

The Progress of the Clinical Investigation into Male Breast Cancer

The median age was from 50 to 65 years old.The etiology remained poorly understood, but the imbalance of endocrineis the commonest factor. The first symptom usually is to discover the painless node and the main histological type is the invasive ductal carcinoma. The ER and PR receptors were positive in most patients,and the lymphatic axilla became the most important prognostic index. The optimal treatment for male breast cancer was ectomy combined with radiotherapy, chemotherapy and endocrintherapy.