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胃食管反流与特发性肺纤维化之间相关性探讨
引用本文:陈石,张德平. 胃食管反流与特发性肺纤维化之间相关性探讨[J]. 国际呼吸杂志, 2008, 28(13): 825-828
作者姓名:陈石  张德平
作者单位:南京大学医学院附属鼓楼医院呼吸内科,210008
摘    要:特发性肺纤维化(idiopathic pulmonary fibrosis,IPF)是一种不断进展的间质性肺疾病.很多实验室证据提示胃酸与肺纤维化有关,进一步的临床观察也发现IPF患者有着高得惊人的食管异常酸反流,且很多人没有胃食管反流的典型症状,这意味着胃食管反流病可能是一个常常被人们忽视的IPF潜在的病理性作用因子.

关 键 词:特发性肺纤维化  胃食管反流病  误吸

Approach about correlation of gastroesophageal reflux and idiopathic pulmonary fibrosis
CHEN Shi,ZHANG De-ping. Approach about correlation of gastroesophageal reflux and idiopathic pulmonary fibrosis[J]. International Journal of Respiration, 2008, 28(13): 825-828
Authors:CHEN Shi  ZHANG De-ping
Abstract:Idiopathic pulmonary fibrosis(IPF)is a progressive interstitial lung disease.Many preclinical evidences demonstrated the correlation between gastric acid and lung fibrosis.Further study indicated that individuals with IPF have a high prevalence of abnormal esophageal acid exposure,usually without typical gastroesophageal reflux symptoms.This means gastroesophageal reflux disease may have underlying pathology that is usually ignored.
Keywords:Idiopathic pulmonary fibrosis  Gastroesophageal reflux disease  Aspiration
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