Discriminant analysis of ultrasonic texture data in diffuse alcoholic liver disease: 1. Fatty liver and cirrhosis |
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| Affiliation: | 1. Center for Ultrasound Research and Translation, Massachusetts General Hospital, Boston, MA, USA;2. Joint Department of Physics, Institute of Cancer Research and Royal Marsden NHS Foundation Trust, London, UK;3. Instituto de Física, Universidad Nacional Autónoma de México, México City, México;4. Verasonics Inc., Kirkland, WA, USA;5. Department of Radiology, King''s College Hospital, London, UK;6. Vave Health, San Jose, CA, USA;7. Department of Radiology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA;2. Hepatology Dept., University Clinic for Visceral Surgery and Medicine, Inselspital, University Hospital of Bern, University of Bern, Switzerland;3. Department of Radiology, Northeastern Ohio Medical University, Rootstown, Ohio, USA;4. Department of Radiology, Chung-Ang University Hospital, Seoul, Korea;5. Department of Medical Ultrasound, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China;11. Department of Radiology, Seoul National University Hospital, Seoul, Republic of Korea;12. Department of Gastroenterology and Hepatology, International University of Health and Welfare, Sanno Hospital, Tokyo, Japan;8. Unit of Internal Medicine, Hepatobiliary and Immunoallergic Diseases, Department of Medical and Surgical Sciences, University of Bologna S. Orsola-Malpighi Hospital, Bologna, Italy;9. Department of Gastroenterology and Hepatology, Tokyo Medical University, Japan;1. Department of Clinical, Surgical, Diagnostic and Pediatric Sciences, University of Pavia, Pavia, Italy;2. Department of Radiology, Northeastern Ohio Medical University, Rootstown, Ohio, USA;3. Southwoods Imaging, Youngstown, Ohio, USA;4. Department of Visceral Surgery and Medicine, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland;5. Division of Gastroenterology and Hepatology, Department of Internal Medicine II, Center for Advanced Research in Gastroenterology and Hepatology, “Victor Babeș” University of Medicine and Pharmacy, Timișoara, Romania;6. Medical Data Analytics Centre, Department of Medicine and Therapeutics, Chinese University of Hong Kong, Hong Kong, China;7. State Key Laboratory of Digestive Disease, Institute of Digestive Disease, Chinese University of Hong Kong, Hong Kong, China;8. Division of Gastroenterology and Hepatology, Department of Medicine III, Medical University of Vienna, Vienna, Austria;9. Christian-Doppler Laboratory for Portal Hypertension and Liver Fibrosis, Medical University of Vienna, Vienna, Austria;10. Division of Gastroenterology, Department of Medicine II, Leipzig University Medical Center, Leipzig, Germany;11. Center for Liver Research, Department of Gastroenterology and Hepatology, Odense University Hospital, Odense, Denmark;12. Department for Clinical Research, University of Southern Denmark, Odense, Denmark;13. Hepatology Division, School of Medicine, Federal University of Rio de Janeiro, Clementino, Fraga Filho Hospital, Rua Prof. Rodolpho Paulo Rocco, Cidade Universitária da Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil;14. Department of Gastroenterology and Hepatology, Fiona Stanley Hospital, Murdoch, Western Australia, Australia;15. Medical School, University of Western Australia, Crawley, Western Australia, Australia;p. Curtin Medical School, Curtin University, Kent Street, Bentley, Western Australia, Australia;q. Université Paris-Cité, Inserm UMR1149, Centre de Recherche sur l''Inflammation, Paris, France;r. Service d''Hépatologie, Hôpital Beaujon, Assistance-Publique Hôpitaux de Paris, Clichy, France;s. Department Allgemeine Innere Medizin (DAIM), Kliniken Hirslanden Beau Site, Salem and Permancence, Bern, Switzerland;t. Division of Hepatobiliary and Pancreatic Disease, Department of Gastroenterology, Hyogo Medical University, Nishinomiya, Hyogo, Japan;u. Ultrasound Imaging Center, Hyogo Medical University, Nishinomiya, Hyogo, Japan;v. Department of Radiology, Seoul National University Hospital, College of Medicine, Seoul National University, Seoul, Republic of Korea;w. Department of Gastroenterology, Alfred Hospital, Melbourne, Australia;x. Department of Medicine, Central Clinical School, Monash University, Melbourne, Australia;y. Gastroenterology Department, Laboratório de Investigação (LIM07), Hospital das Clínicas de São Paulo, HCFMUSP, Faculdade de Medicina, Universidade de São Paulo, São Paulo, Brazil;z. Department of Hepatology, Institute of Liver and Biliary Sciences, Vasant Kunj, New Delhi, India |
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| Abstract: | In previous work by our group, it has been shown that the use of texture analysis on digitally recorded radio-frequency ultrasonic signals can provide useful diagnostic information in diffuse liver disease. A rigorous multivariate analysis and the addition of new texture parameters has confirmed the efficacy of the technique. Discriminant functions have been produced to provide excellent accuracies in the detection of diffuse liver disease. |
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