| CEA、CYFRA21-1和NSE联检对恶性胸腔积液的诊断价值 |
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| 引用本文： | 陈晓笑.CEA、CYFRA21-1和NSE联检对恶性胸腔积液的诊断价值[J].放射免疫学杂志,2008,21(6):494-495. |
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| 作者姓名： | 陈晓笑 |
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| 作者单位： | 南通大学第二附属医院呼吸科,226001 |
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| 摘 要： | 目的：探讨CEA、CYFRA21-1和NSE联检对恶性胸腔积液的诊断价值。方法：采用放射免疫分析检测了40例恶性胸腔积液（恶性组）和32例结核性胸腔积液（结核组）血清和胸腔积液的CEA、CYFRA21-1和NSE的水平并计算其胸腔积液/血清（P/S）比值。结果：恶性胸腔积液组中胸腔积液CEA、CYFRA21-1和NSE水平及P/S比值明显高于结核组（P〈0.01）。CEA、CYFRA21-1和NSE单项检测恶性胸腔积液特异性最高的为CEA（90）,敏感性最高为CYFRA21-1（83）。CEA、CYFRA21-1和NSE三项联检对恶性胸腔积液的敏感性为90,特异性为89。结论：CEA、CYFRA21-1和NSE三项肿瘤标志物联检可明显提高恶性胸腔积液的阳性诊断率,对恶性胸腔积液的诊断有较高的临床应用价值。
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| 关 键 词： | 癌胚抗原 细胞角蛋白片段 神经元特异性烯醇化酶 恶性胸腔积液 |
Diagnostic Value of Combined Determination of Serum and Pleural Effusion CEA,CYFRA21-1 and NSE Levels in Patients with Malignancy |
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| Chen Xiaoxiao.Diagnostic Value of Combined Determination of Serum and Pleural Effusion CEA,CYFRA21-1 and NSE Levels in Patients with Malignancy[J].Journal of Radioimmanology,2008,21(6):494-495. |
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| Authors: | Chen Xiaoxiao |
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| Institution: | Chen Xiaoxiao Second Affiliated Hospital of Nantong University,Nantong,Jiangsu(226001) |
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| Abstract: | Objective To study the clinical value of combined determination of serum and pleural effusion levels of CEA,CYFRA21-1 and NSE in patients with malignancy.Methods Serum and pleural effusion CEA,CYFRA21-1 and NSE levels were measured with RIA in 40 patients with malignant and 32 patients with tuberculous pleural effusions.Results The pleural effusion CEA,CYFRA21-1,NSE levels and pleural effusion serum levels ratio in maligant group were significantly higher than those in tuberculous group(P<0.01).The specific... |
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| Keywords: | CEA CYFRA21-1 NSE malignant pleural effusion |
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