| 中线T细胞淋巴瘤与EB病毒关系的观察 |
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| 引用本文： | 万榕 高美钦. 中线T细胞淋巴瘤与EB病毒关系的观察[J]. 肿瘤研究与临床, 1998, 10(4): 231-233 |
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| 作者姓名： | 万榕 高美钦 |
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| 作者单位： | 福建医科大学 |
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| 摘 要： | 为研究中线Ｔ细胞淋巴瘤（ＭＴＬ）与ＥＢ病毒的关系，运用原位杂交和免疫组化技术检测２０例中线Ｔ细胞淋巴瘤，观察其ＥＢ病毒的存在情况，结果２０例ＭＴＬ均显示Ｔ细胞标记阳性，Ｂ细胞标记阴性；原位杂交ＥＢ病毒（ＥＢＥＲ－１）阳性率７０％（１４／２０），ＬＭＰ－１检出率５０％（１０／２０），结果表明ＥＢ病毒感染与ＭＴＬ存在密切关系，可能在其发病中起着重要作用
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| 关 键 词： | Epstein－Barr病毒 T细胞淋巴瘤 原位杂交 免疫组化 |
OBSERVATION ON THE ASSOCIATION BETWEEN EPSTEIN BARR VIRUS AND MIDLINE T CELL LYMPHOMA |
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| Wan Rong,Gao Meiqin,Gao Lingyun,et al Fujian Medical University. OBSERVATION ON THE ASSOCIATION BETWEEN EPSTEIN BARR VIRUS AND MIDLINE T CELL LYMPHOMA[J]. Cancer Research and Clinic, 1998, 10(4): 231-233 |
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| Authors: | Wan Rong Gao Meiqin Gao Lingyun et al Fujian Medical University |
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| Abstract: | To study the relationship between midline T cell lymphoma(MTL) and Epstein Barr Virus(EBV),in situ hybridization and immunohistochemical methods were used to detect EBER 1 and latent membrane protein 1(LMP 1) on paraffin embedded tissues of 20 MTL cases.The postive rate of EBER 1 in 20 cases of MTL were 70%(14/20), LMP 1 expression was detected in 50%(10/20) of MTL. Our results suggested that EBV infection may have some relationship with the genesis of MTL. |
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| Keywords: | Epstein Barr virus T cell lypmhoma In situ hybridization Immunohistochemistry |
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