23例中药联合胰岛素治疗2型糖尿病的临床疗效分析

目的探讨中药联合胰岛素治疗2型糖尿病（T2DM）减低HbA1c的水平。方法对23例初诊T2DM患者作为联合组,采用中药联合胰岛素强化治疗,20例空腹血糖值相同者（对照组）单纯胰岛素治疗作为对照组,疗程3个月,采用SPSS16.0进行统计分析,比较2组在患病结局、血糖控制、糖化血红蛋白（HbA1c）水平之间的差异。结果治疗前2组空腹血糖和餐后2h血糖水平差异无统计学意义（P〉0.05）,治疗2周后差异有统计学意义（P〈0.05）。治疗前2组HbA1c水平差异无统计学意义（P〉0.05）,治疗3个月后2组差异有统计学意义（P〈0.05）。结论中药胰岛素治疗T2DM相比于单纯胰岛素治疗可获得更好血糖控制。

23 Cases of the Traditional Chinese Medicine Combined Insulin Treatment for Type 2 Diabetes of the Clinical Effect of Analysis

Objective To compare the level of HbA1cl in insulin-requiring patients with diabetes treated twice daily with Chinese herbal remedies （CHR） combined with insulinvs.insuli）.Methods The study cohort of 43 patient with type 2 diabetes used a two-way,crossover design.The patients （n=23） with type 2 diabetes （the combined group） were treated with CHR combined withCSII,and the patients（n=20） with the same fasting p lasma glucose value （the control group） were treated with CSII only.Fasting blood glucose （FBG）,haemoglobin A1c （HbA1c）,insulin dose,rate of hypoglycaemia and safety data were obtained and analyzed by SPSS.Results Mean 2-h PPBG and FBG decreased significantly at end-point in the combined groupas compared with human insulin mix 50（P〈0.05）.The HbA1c excursion（P〈0.001） were significantly lower after 3 months（P〈0.05）.Conclusion CHR combined with insulin pump cancontrol p lasma glucose well in the treatment of type 2 diabetes.