七氟醚和异氟醚吸入麻醉用于全子宫切除术的麻醉效果观察

目的观察并比较七氟醚和异氟醚吸人麻醉用于全子宫切除术的麻醉效果。方法120例行择期全子宫切除术的女性患者随机分为七氟醚和异氟醚各60例，麻醉诱导后分别吸入七氟醚和异氟醚麻醉。观察并记录诱导前（T0）、插管5min后（T1）、切皮（T2）、睁眼时（T3）和拔管前（T4）患者的HR、MAP和SpO2。观察并记录患者的睁眼时间和拔管时间。结果七氟醚和异氟醚组T0、T1、T2、T3和T4时刻的HR、MAP和SpO2比较，差异均无统计学意义（P〉0．05）。七氟醚和异氟醚组的睁眼时间分别为（7．2±2．5）min和（12．6±3．2）min，差异具有统计学意义（P〈O．05）；两组拔管时间分别为（8．7±2．8）min和（14．3±3．6）min，差异具有统计学意义（P〈0．05）。结论七氟醚和异氟醚吸人麻醉用于全子宫切除术麻醉，对患者的生命体征均无明显影响，但七氟醚组术后苏醒时间更快。

Effects of Sevoflurane and Isoflurane Inhaled Anesthesia on Total Hysterectomy

Objective To observe and compare the effect of sevoflurane and isoflurane inhaled anesthesia on total hysterectomy. Methods One hundred twenty cases of patients treated with total hysterectomy were randomly divided into sevoflurane group （ n = 60 ） and isoflurane group （n = 60 ）. After the induction of anesthesia they were inhaled sevoflurane and isoflurane for general anesthesia, respectively. The HR, MAP and SpO2were evaluated of the two groups at the moment at before induction（ T0 ）, 5 min after intubation （ T1 ）, trotting skin （ T2 ）, eye open （ T3 ） and before decannulation （ T4 ）. Results The HR, MAP and SpO2 produced no difference between the two groups at T0, T1, T2, T3 and T4. The time of eye open in sevoflurane group was （ 7.2 ± 2.5 ） min, shorter than （ 12.6 ± 3.2 ） min of isoflurane group （P 〈 0.05 ） ; The time of decannulation was （ 8.7 ± 2.8 ） min in sevoflurane group, shorter than （ 14.3 ± 3.6 ） min of isoflurane group （ P 〈 0.05 ）. Conclusion Sevoflurane and isoflurane inhaled anesthesia both produce no influence on vital signs, but the cases in sevoflurane group wake sooner after total hysterectomy.