Antitussive potential of methanol extract of stem bark of Ficus racemosa Linn |
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Authors: | Bhaskara Rao R Murugesan T Pal M Saha B P Mandal S C |
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Institution: | Sultan UI Uloom College of Pharmacy, 'Mount Pleasant' 8 2 249, Road No. 3, Banjara Hills, Hyderabad 500 034, A.P. India. bhaskaranu@yahoo.com |
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Abstract: | The methanol extract of Ficus racemosa Linn (Moraceae) (stem bark) (MEFR) was tested for its antitussive potential against a cough induced model by sulphur dioxide gas in mice. The extract demonstrated significant (p < 0.001) antitussive activity at all tested dose levels when compared with the control. The antitussive activity of the extract was comparable to that of codeine phosphate (10 mg), a standard antitussive agent. The extract exhibited maximum inhibition of 56.9% at a dose of 200 mg/kg (p.o.) 90 min after administration. |
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Keywords: | Ficus racemosa antitussive MEFR cough |
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