| 脉复生对动脉硬化闭塞症患者血脂及炎症细胞因子的影响 |
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| 引用本文： | 李顺宁.脉复生对动脉硬化闭塞症患者血脂及炎症细胞因子的影响[J].云南中医中药杂志,2011,32(11). |
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| 作者姓名： | 李顺宁 |
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| 作者单位： | 广东省广州市中医医院脉管炎科,广州广东,510130 |
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| 基金项目： | 广州市卫生局中医科研课题 |
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| 摘 要： | 目的:观察脉复生对动脉硬化闭塞症患者血脂及炎症细胞因子的影响,探讨其抗动脉粥样硬化的机制.方法:将120例患者采用随机对照原则分为2组,对照组60例,给予常规抗感染、控制血压、降糖、抗凝、改善循环、支持疗法等基础治疗.治疗组60例,在基础治疗上加脉复生口服.每日2次,每次50 mL.在治疗前后分别抽取患者外周血,用于测定患者血脂6项( CHOL、TG、LDL、HDL、APOA、APOB)水平及CRP、IL-6、TNF-α,ICAM-1等细胞因子含量,比较自身前后变化及2组之间的差异.结果:治疗组治疗前、后相比,血脂水平有所下降(P＜0.05),有统计学意义;治疗后,治疗组在降低TC、TG、LDL、APOB指标方面,与对照组比较,有统计学意义(P＜0.05),但在升高HDL、APOA指标方面无明显统计学差异.脉复生治疗组内治疗前、后CRP、IL一6、TNF-a、ICAM-1相比均有显著性差异(P＜0.01,P＜0.05);治疗后,治疗组与对照组CRP、IL-6、TNF-a、ICAM-1相比均有显著性差异(P＜0.05),治疗组优于对照组.结论:脉复生在调节血脂代谢,降低CRP等炎症因子,抗动脉血管炎症反应,抑制单核细胞与血管内皮细胞的黏附方面有良好作用,能抑制动脉硬化闭塞症的发生发展,对动脉硬化闭塞症具有较好的治疗效果.
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| 关 键 词： | 动脉硬化闭塞症 脉复生 血脂 炎症细胞因子 |
Impact of Pulse resuscitation on the Lipids and Inflammatory Cytokines of Arteriosclerosis Obliterans Patients |
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| LI Shun-ning.Impact of Pulse resuscitation on the Lipids and Inflammatory Cytokines of Arteriosclerosis Obliterans Patients[J].Yunnan Journal of Traditional Chinese Medicine and Materia Medica,2011,32(11). |
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| Authors: | LI Shun-ning |
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| Institution: | LI Shun-ning(Vasculitis Section,Traditional Chinese Medical Hospital of Guangzhou City Guangzhou,Guangdong,510130) |
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| Abstract: | Objective: To observe the impact of pulse resuscitation on the Lipids and inflammatory cytokines of arteriosclerosis obliterans patients and to explore its anti-atherosclerotic mechanisms.Methods: 120 patients were randomly divided into one treatment group and one control group,60 patients per group.The control group was treated with conventional basic treatment such as antibiotics,blood pressure control,blood glucose lowering,anti-coagulation,circulation improvement,supportive therapy.The treatment group w... |
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| Keywords: | arterial occlusive disease pulse resuscitation lipids inflammatory cytokines |
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