| 应用3种抗原的芯片系统检测结核分枝杆菌 |
| |
| 引用本文： | 周正康,顾国浩,史进方,李忆,吴兴福,胥萍,钱雪峰,高纯. 应用3种抗原的芯片系统检测结核分枝杆菌[J]. 苏州大学学报(自然科学版), 2006, 26(5): 751-753 |
| |
| 作者姓名： | 周正康 顾国浩 史进方 李忆 吴兴福 胥萍 钱雪峰 高纯 |
| |
| 作者单位： | [1]苏州大学附属第一医院检验科,江苏省临床免疫学重点实验室 [2]苏州大学附属第一医院肺科,江苏苏州215006 [3]苏州市第五人民医院,江苏苏州215007 |
| |
| 摘 要： | 目的 探讨3种抗原的芯片系统检测结核分枝杆菌的敏感性及特异性。方法 以3种结核抗原的芯片检测系统，对临床确诊的100例肺结核标本及100例非结核标本进行检测。结果 芯片检测的敏感度为88％，两项或三项指标同时阳性时，特异度可达100％；芯片检测结核组与非结核组结果有高度显著性差异（P〈0．01）。结论 结核分枝杆菌3种抗原的芯片敏感性高、特异性强。
|
| 关 键 词： | 结核分枝杆菌 抗原芯片 |
| 文章编号： | 1673-0399(2006)05-0751-03 |
| 收稿时间： | 2005-11-07 |
| 修稿时间： | 2005-11-07 |
Analyzing Mycobacterium Tuberculosis with Three Antigens Chip System |
| |
| ZHOU Zheng-kang, GU Guo-hao, SHI Jin-fang, et al. Analyzing Mycobacterium Tuberculosis with Three Antigens Chip System[J]. Suzhou University Journal of Medical Science, 2006, 26(5): 751-753 |
| |
| Authors: | ZHOU Zheng-kang GU Guo-hao SHI Jin-fang et al |
| |
| Affiliation: | Department of Clinical Laboratory, The First Hospital Affiliated to Suzhou University, Jiangsu Key Laboratory for Clinical Immunology , Jiangsu Suzhou 215006, China |
| |
| Abstract: | Objective To discuss the sensitivity and specificity of three antigens chip system in detecting mycobacterium tuberculosis.Method One hundred pulmonary tuberculosis and 100 non-pulmonary tuberculosis serum samples were analyzed respectively with three antigens chip system.Results The chip system sensitivity in detecting mycobacterium tuberculosis was 88%,the specificity achieved to 100% when two or three items were positive simultaneously.Significant difference existed between pulmonary tuberculosis and non-pulmonary tuberculosis when analyzed with this chip system(P<0.01).Conclusion Three antigens chip system is sensitive,specific,simple,accurate and will be valuable in clinical applications. |
| |
| Keywords: | mycobacterium tuberculosis antigen chip system |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ |
