| 口服芳维A酸乙酯联合窄谱中波紫外线照射治疗寻常型银屑病的临床研究 |
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| 引用本文： | 吴军,张国威,何威,何云志,黄海,王儒鹏,黎智.口服芳维A酸乙酯联合窄谱中波紫外线照射治疗寻常型银屑病的临床研究[J].重庆医学,2008,37(12):1280-1281. |
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| 作者姓名： | 吴军 张国威 何威 何云志 黄海 王儒鹏 黎智 |
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| 作者单位： | 第三军医大学新桥医院皮肤科,重庆,400037;第三军医大学新桥医院皮肤科,重庆,400037;第三军医大学新桥医院皮肤科,重庆,400037;第三军医大学新桥医院皮肤科,重庆,400037;第三军医大学新桥医院皮肤科,重庆,400037;第三军医大学新桥医院皮肤科,重庆,400037;第三军医大学新桥医院皮肤科,重庆,400037 |
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| 摘 要： | 目的观察芳维A酸乙酯联合窄谱中波紫外线(NB-UVB)照射治疗寻常型银屑病的临床疗效及影响因素。方法口服芳维A酸乙酯联合NB-UVB照射328例寻常型银屑病,单独采用NB-UVB照射治疗279例寻常型银屑病。以银屑病皮损面积和严重指数(PASI)评价疗效,并纪录不良反应。结果单独采用NB-UVB治疗寻常型银屑病有效,而口服芳维A酸乙酯联合NB-UVB照射则可显著提高疗效、缩短治疗时间且安全。结论口服芳维A酸乙酯联合NB-UVB照射治疗寻常型银屑病可取得良好疗效,不良反应小。
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| 关 键 词： | 芳维A酸乙酯 窄谱中波紫外线 寻常型银屑病 |
Clinical study of arotinoid ethylester combined with narrow-band ultraviolet B in treating psoriasis vulgaris |
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| WU Jun,ZHANG Guo-wei,HE Wei,et al..Clinical study of arotinoid ethylester combined with narrow-band ultraviolet B in treating psoriasis vulgaris[J].Chongqing Medical Journal,2008,37(12):1280-1281. |
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| Authors: | WU Jun ZHANG Guo-wei HE Wei |
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| Abstract: | Objective To observe the therapeutic effect of oral arotinoid ethylester combined with narrow-band ultraviolet B(NB-UVB) phototherapy for psoriasis vulgaris.Methods A total of 607 patients with psoriasis vulgaris were treated by NB-UVB phototherapy only or oral arotinoid ethylester combined with NB-UVB phototherapy for 8 weeks.The efficacy was assessed according to the change in PASI score and the adverse events were recorded.Results NB-UVB phototherapy plus arotinoid ethylester was more effective than NB-UVB phototherapy alone in the treatment of psoriasis vulgaris.Conclusion Oral arotinoid ethylester combined with NB-UVB phototherapy is effective and safe in the treatment of psoriasis vulgaris. |
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| Keywords: | psoriasis vulgaris arotinoid ethylester narrow-band ultraviolet B |
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