阻塞性睡眠呼吸暂停低通气综合征对不同年龄组患儿睡眠结构的影响

目的:了解阻塞性睡眠呼吸暂停低通气综合征(OSAHS)对不同年龄组患儿睡眠结构的影响。方法:将133例2~12岁确诊为OSAHS的患儿分为学龄前组和学龄组,进行PSG,记录睡眠各期比例、睡眠效率、AHI、觉醒指数、最低SaO2,并对结果进行统计学分析。结果:学龄前组和学龄组患儿之间睡眠效率(88.0±4.0,94.1±1.3)%,睡眠Ⅰ期(14.2±2.5,10.6±1.9)%,睡眠Ⅱ期(40.15±4.6,46.5±2.4)%,慢波睡眠(27.4±6.4,18.5±1.7)%,快动眼睡眠(REM)(17.7±3.0,22.3±2.0)%,AHI(5.9±1.3,7.7±2.6),觉醒指数(18.3±3.5,22.4±2.7),最低SaO2(87.2±2.1,90.1±0.8),均差异无统计学意义(均P>0.05)。结论:在OSAHS状态下,学龄前组和学龄组患儿的睡眠结构具有相似性,学龄前期患儿比学龄期患儿具有明显的REM剥夺现象。

Effects of sleep architecture in different age children with obstructive sleep apnea syndrome

OBJECTIVE: To explore how obstructive sleep apnea syndrome(OSAHS) affects different age children's sleep architecture. METHOD: One hundred and thirty three OSAHS children which divided into preschool age group and school age group, were monitored with polysomnography for 7 hours at night, sleep efficiency, stage I %, stage II %, SWS%, REM%, apnea/hypopnea index, arousal index and nadir O2 desaturation were recorded and analyzed. RESULT: Between preschool age group and school age group, sleep efficiency (88.0% +/- 4.0%) versus 94.1% +/- 1.30%), stage I% (14.2 +/- 2.5 versus 10.6 +/- 1.9), stage II% (40.15 +/- 4.6 versus 46.5 +/- 2.4), SWS% (27.4 +/- 6.4 versus 18.5 +/- 1.7), REM% (17.7 +/- 3.0 versus 22.3 +/- 2.0), apnea/hypopnea index (5.9 +/- 1.3 versus 7.7 +/- 2.6), arousal index (18.3 +/- 3.5 versus 22.4 +/- 2.7), nadir O2 desaturation (87.2 +/- 2.1 versus 90.1 +/- 0.8), the difference between preschool age group and school age group did not reach statistical significance. CONCLUSION: Under the state of obstructive sleep apnea syndrome (OSAHS) preschool age group and school age group have similar sleep architecture, and preschool age group have more "REM deprivation" than school age group.