| 细胞凋亡相关新基因TFAR19(PDCD5)研究进展 |
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| 引用本文： | 李红艳,刘永明.细胞凋亡相关新基因TFAR19(PDCD5)研究进展[J].华夏医学,2004,17(3):459-461. |
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| 作者姓名： | 李红艳 刘永明 |
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| 作者单位： | 桂林医学院生物化学与分子生物学教研室,广西,桂林,541004 |
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| 摘 要： | 细胞凋亡是在一定的生理或病理条件下。由基因控制的细胞自我毁灭过程。凋亡异常与许多疾病(尤其是肿瘤)的形成及发展进程密切相关。细胞凋亡调控机制研究证明。多种基因(如P53、C-myc、Bcl-2、Bax等)参与了细胞凋亡的调控过程。TFAR19基因是由我国科研人员最近新发现的另一重要的凋亡相关基因，笔者主要就其结构特点、性质功能、临床意义作一概述。
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| 关 键 词： | 细胞凋亡 凋亡调控 TFAR19基因 结构特点 性质功能 胚胎发育 |
| 文章编号： | 1008-2409(2004)03-0459-03 |
| 修稿时间： | 2004年1月9日 |
Recent advances of a new apoptosis Gene TFAR19(PDCD5) |
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| LI Hong yan Guilin Medical College,Guilin ,China.Recent advances of a new apoptosis Gene TFAR19(PDCD5)[J].Acta Medicinae Sinica,2004,17(3):459-461. |
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| Authors: | LI Hong yan Guilin Medical College Guilin China |
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| Institution: | LI Hong yan Guilin Medical College,Guilin 541004,China |
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| Abstract: | Apoptosis is the destroy process of cell self on condition that physiology or pathology under the control of gene. The abnormality of apoptosis nearly correlates with the process of forming and developing many diseases,especially tumour. The research about the mechanism of apoptosis regulation proves that many genes(for example P53,C myc,Bcl 2,Bax and so on) participate in the process of apoptosis regulation. TFAR19 is another new important apoptosis gene, which is recently discovered in our country. The article reviews this new gene a brief on its structure, character, function and clinical significance. |
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| Keywords: | apoptosis apoptosis regulation TFAR 19 |
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