| Curative effect of heat-sensitive moxibustion on chronic persistent asthma： a multicenter randomized controlled trial |
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| 作者单位： | [1]Department of Acupuncture and Rehabilitation,Hospital Affiliated to Jiangxi University of Traditional Chi-nese Medicine, Nanchang 330006, China [2]Department of Rehabilitation, Guangdong Hos-pital of Combination of Traditional Chinese Medicine withWestern Medicine, Foshan 528000, China [3]Department of Pneumology, Guangdong Hos-pital of Traditional Chinese Medicine, Guangzhou 519015,China [4]Department of Acupuncture, First Hospitalof Wuhan, Wuhan 430032, China [5]Institute of Acupuncture and Massage, Guang-zhou University of Traditional Chinese Medicine, Guang-zhou 510405, China [6]Department of Pneumology, First Hospital Affili-ated to Nanchang University, Nanchang 330006, China [7]Department of Rehabilitation, First Hospi-tal Affiliated to Chongqing Medical University, Chongqing400016, ChinaZhpn W~na. I＇）en~rtmpnt nf ArHnHnctHrp. First Hn~nital Af- [8]Department of Acupuncture, First Hospital Af-filiated to Zhejiang University of Traditional Chinese Medi-cine, Hangzhou 310018, China [9]Department of Acupuncture, Suzhou Hospital ofTCM, Suzhou 215003, China [10]Department of Acupuncture, Hospital Affiliatedto Shandong University of Traditional Chinese Medicine, Ji-nan 25001 ~, China [11]Department of Acupuncture, Guangdong Dis-abled Soldier Hospital, Guangzhou 510260, China [12]Department of Acupuncture, NanchangHospital of combination of Traditional Chinese Medicinewith Western Medicine, Nanchang 330003, China |
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| 基金项目： | Supported by the Major State Basic Research and Development Program of People＇s Republic of China（No.2009CB522902）;; National Key Technology R＆D Program（No.2006BAI12B04-2）;; National Natural Science Foundation of China（No.81160453）;National Natural Science Foundation of China（No.81202854）;; Jiangxi Key R＆D Project |
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| 摘 要： | OBJECTIVE： To compare the curative effects of heat-sensitive moxibustion with conventional drugs on chronic persistent asthma and seek a valuable therapy to replaceWestern Medicine. METHODS： The participants in this multi-center, randomized, and controlled study were randomly divided into two groups： group A（n=144）, treated with heat-sensitive moxibustion（50 sessions） and group B（n=144）, treated with Seretide（salmeterol 50 μg/fluticasone 250 μg, twice a day）. The scores of asthma control test（ACT）, forced expiratory volume in 1 second（FEV1）, peak expiratory flow（PEF）, and attack frequency were measured after 15, 30, 60, and 90 days of treatment. Patients followed up 3 and 6 months after treatment. RESULTS： There was a significant difference（P= 0.0002） in the ACT score and lung function between the two groups after 3 months of treatment and（P=0.000 03） during the follow-up visits. In addition, heat-sensitive moxibustion reduced attack frequency in the period from inclusion to the 6-month follow-up visit. CONCLUSION： This study shows that heat-sensitive moxibustion may have a comparable curative effect toSeretide（salmeterol/fluticasone） on asthma.
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| 关 键 词： | 随机对照试验 热敏感 持续性 多中心 哮喘 疗效 慢性 频率测量 |
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