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TLR9 turns the tide on Treg cells
Authors:Mills Kingston H G
Affiliation:School of Biochemistry and Immunology, Trinity College, Dublin 2, Ireland. kingston.mills@tcd.ie
Abstract:In this issue of Immunity, Hall et al. (2008) demonstrate that commensal bacterial DNA can suppress Treg cell conversion via TLR9-mediated activation of lamina propria dendritic cells and thus potentially disrupt intestinal homeostasis.
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