弓形虫感染所致慢性荨麻疹45例治疗分析

目的探讨弓形虫感染与慢性荨麻疹的关系。方法血清弓形虫抗体检测阳性的慢性荨麻疹患者45例,其中25例口服乙酰螺旋霉素治疗,20例口服特非那丁治疗。结果乙酰螺旋霉素治疗组开始起效时间(5~6 d)慢于特非那丁治疗组(2~3 d),但乙酰螺旋霉素治疗组治愈率和有效率(68%、92%)均高于特非那丁治疗组(15%、60%)(χ2=33.843,χ2=6.737,P<0.01)。结论血清弓形虫抗体阳性的慢性荨麻疹患者使用乙酰螺旋霉素治疗,疗效显著。

Analysis of clinical treatment of 45 patients with chronic urticaria induece by toxoplasma infection

Objective To explore the relationship between toxoplasma infection and chronic urticaria.Methods Forty-five chronic urticaria patients with positive serum toxoplasma,among of these 25 cases were orally administered with acetyl spiramycin and 20 cases received oral administration with terfenadine.Results starting to show effect in the acetyl spiramycin group (5～6d) was later than that in the terfenadine group(2～3d).However,the recovery rate and effective rate in the acetyl spiramycin group(68%,92%) were higher than those in the terfenadine group(15%,60%)(χ~2=33.843,χ~2=6.737,P<0.01).Conclusion Acetyl spiramycin shows significant efficacy on chronic urticaria patients with positive serum toxoplasma.