冠脉内支架植入术治疗急性冠脉综合征65例临床分析

目的探讨经皮冠状动脉腔内成形术和支架植入术治疗急性冠脉综合征的近期和远期疗效.方法对65例急性冠脉综合征患者在经过内科常规治疗后心绞痛仍不缓解,即行冠状动脉造影,明确病变后行经皮冠状动脉腔内成形术和支架植入术,术前术后进行抗血栓治疗,抗血栓药物包括阿斯匹林、塞氯匹啶或氯比格雷、皮下注射低分子肝素钙针.结果介入治疗病例、病变成功率分别是93.8%(61/65)和93.1%(108/116).1例因右冠状动脉夹层发生死亡,无急性心肌梗死,急诊冠状动脉搭桥术.60例介入治疗均获成功,50例心绞痛完全消失,10例有不典型胸痛,症状在2~3 d内消失.随诊3~54个月,6例发生心脏事件,其中1例死亡,1例发生心肌梗死,4例再次行血管重建治疗(介入治疗2例,冠状动脉旁路移植术2例).结论在使用抗血栓药物包括阿斯匹林、塞氯匹啶或氯比格雷、皮下注射低分子肝素钙针的前提下,经皮冠状动脉腔内成形术和支架植入术治疗急性冠脉综合征的近期疗效明显,远期疗效满意.

Percutaneous Coronary Angioplasty and Stenting for Treatment of Acute Coronary Syndrome

Objective To investigate the short and longterm effect of the treatment on acute coronary syndrome(ACS) with percutaneous coronary angioplasty and stenting.Methods 65 patients suffering from ACS were treated with angiography to illuminate the features of lesions and proceeded with percutaneous coronary angioplasty and stenting when the angina was not completed controlled with internal medicine.All patients were treated with a new anti-thrombotic regimen,including aspirin,ticlopidine or clopidogrel, and low-molecular-weight heparin.Results The rates of success for patients and lesions were 96.9% and 82.7% respectively.One patient died without myocardial infarction or emergency bypass surgery.56 patients had no symptom of angina after procedure,and 5 patients had non-typical chest pain which disappeared within 2~3 days.During the 3~54 month follow-up,one patient died,one patient developed myocardial infarction and 4 patients underwent target vessel revascularization(repeated angioplasty 2 and bypass surgery 2).Conclusions With the widespread use of aspirin-ticlopidine-low molecular heparin regimen,ACS patients can undergo PTCA and stenting with high success rate,excellent immediate efficacy and long-term efficacy.