| CLINICAL EFFICACY OF VINORELBINE PLUS CISPLATIN IN ADVANCED NON-SMALL CELL LUNG CANCER |
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| 引用本文： | 童茂荣,夏锡荣,曹鄂洪,施毅,赵蓓蕾. CLINICAL EFFICACY OF VINORELBINE PLUS CISPLATIN IN ADVANCED NON-SMALL CELL LUNG CANCER[J]. 中国癌症研究, 1996, 8(3): 227-229. DOI: 10.1007/BF02675496 |
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| 作者姓名： | 童茂荣 夏锡荣 曹鄂洪 施毅 赵蓓蕾 |
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| 摘 要： | A clinical study of the efficacy of vinorelbine plus cisplatin regimen in the management of advanced NSCLC was performed in 35 patients. Five of the 35 patients failed to finish one cycle of chemotherapy with this regimen because of severe and intractable leukopenia or rapid progress of the disease. Tumor response and toxicity were evaluated in the remaining 30 cases. Results showed that, with this regimen, the objective response rate (CR PR) was 46.7%. The most common toxicity was leukopenia; other side effects included alopecia, gastrointestinal reactions, slight and transient renal and hepatic impairment and peripheral neuropathy. It suggested that vinorelbine plus cisplatin is a safe and effective regimen in the management of advanced NSCLC.
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| 修稿时间： | 1995-12-28 |
Clinical efficacy of vinorelbine plus cisplatin in advanced non-small cell lung cancer |
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| Tong Maorong,Xia Xirong,Cao Ehong,Shi Yi,Zhao Beilei. Clinical efficacy of vinorelbine plus cisplatin in advanced non-small cell lung cancer[J]. Chinese Journal of Cancer Research, 1996, 8(3): 227-229. DOI: 10.1007/BF02675496 |
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| Authors: | Tong Maorong Xia Xirong Cao Ehong Shi Yi Zhao Beilei |
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| Affiliation: | Tong Maorong Xia Xirong |
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| Abstract: | A clinical study of the efficacy of vinorelbine plus cisplatin regimen in the management of advanced NSCLC was performed in 35 patients. Five of the 35 patients failed to finish one cycle of chemotherapy with this regimen because of severe and intractable leukopenia or rapid progress of the disease. Tumor response and toxicity were evaluated in the remaining 30 cases. Results showed that, with this regimen, the objective response rate (CR PR) was 46.7%. The most common toxicity was leukopenia; other side effects included alopecia, gastrointestinal reactions, slight and transient renal and hepatic impairment and peripheral neuropathy. It suggested that vinorelbine plus cisplatin is a safe and effective regimen in the management of advanced NSCLC. |
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| Keywords: | Vinorelbine Cisplatin Non-small cell lung carcinoma Management. |
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