Vertebral anomalies associated with esophageal atresia and tracheoesophageal fistula with reference to the initial operative mortality |
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Authors: | W Bond-Taylor F Starer J D Atwell |
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Affiliation: | 1. Westminster Children''s Hospital, London, England;2. Southampton Children''s Hospital, Southampton, England |
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Abstract: | In a series of 40 patients with esophageal atresia and tracheoesophageal fistula, the incidence of musculoskeletal anomalies was 45% (18 patients). An extra mesodermal segment was found in 15 patients (13 paired thoracic vertebrae and 13 paired ribs in nine patients; six lumbar vertebrae in 6 patients). The mortality in grade A infants with an extra mesodermal segment was significantly higher than in those infants with a normal spine (p > 0.01). It is suggested that segmentation or abnormal segmentation of the embryo may be important as a cause of esophageal atresia. |
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Keywords: | Address for reprint requests: John Atwell M.B. Ch.B. F.R.C.S. Southampton Children's Hospital Winchester Road Southampton SO9 4WR England. |
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