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非穿透性小梁显微手术的远期疗效观察
引用本文:骆荣江,刘韶瑞,林先轩,林明楷,田臻.非穿透性小梁显微手术的远期疗效观察[J].中国临床实用医学,2009,3(2):36-37.
作者姓名:骆荣江  刘韶瑞  林先轩  林明楷  田臻
作者单位:1. 中山大学附属第一医院,广州,510080
2. 中山大学中山眼科中心,广州,510080
摘    要:目的探讨非穿透性小梁显微手术治疗青光眼的远期疗效。方法对原发性开角型青光眼患者共46例(46眼),随机选择施行非穿透性小梁手术(A组22例,22眼)或穿透性小梁手术(B组24例,24眼),比较两组患者术后的眼压、滤过泡和视野等情况。结果①术后观察近50个月,A组眼压有较明显升高的趋势,眼压控制完全成功仅为5眼(22.73%),失败7眼(31.82%);B组完全成功11眼(45.83%),失败4眼(16.67%),但两组的差异无统计学意义(P〉0.05);②术后所有B组患者均形成明显的功能性滤过泡;A组患者只有15眼(68.18%)形成明显滤过泡,3眼(13.64%)仅见滤床轻度隆起;随着时间的推移,两组患者滤过泡消失的例数显示出明显差异(P〈0.05);③术后50个月的视野改变情况,A组视野缩小者例数为9眼(40.90%),B组为4眼(16.67%),但差异无统计学意义(P=0.068〉0.05)。结论施行非穿透性小梁手术的部分病例远期疗效欠佳,须谨慎选择适应患者,以提高手术成功率。

关 键 词:小梁  显微手术  青光眼  非穿透性

Long-term effects of non-penatrating trabecular surgery treating glaucoma
Abstract:Objective To evaluate the long-term clinical effect of non-penetrating trabecular surgery (NPTS)for the treatment of primary open angle glaucoma(POAG). Methods A total of 46 patients(46 eyes) with POAG were observed retrospectively. 22 eyes and 24 eyes uderwent non-penetrating trabecular surgery (NPTS) and trabeculectomy surgery(TS). Intraocular pressure (IOP), filtration bleb and visual field were ob-served. Results ①In the follow-up of 50 month, there was a significant hypertendency in post-operative intraoc-ular pressure in NPTS group. The IOP was controlled successfully in 5 eyes(22. 73%) ,and 7 eyes(31.82%) were failure in NPTS group. 11 eyes(45.83%) were success,4 eyes(16. 67%) were failure in TS group, but there were no statistically significant differences between two groups(P > 0. 05). ②The ratio of sustained filtra-tion bleb of TS group after surgery is 100% ,the ratio of sustained filtration bleb of NPTS group after surgery is 15 (68.18%), while 3 eyes(13.64%)were flat filtrtion hleb. From the time passing by, there were statistically significant differences in the disappearance number of filtration bled between two groups (P < 0. 05). ③After 50 month ,9 eyes (40. 90%) were constriction of fields in NPTS group, while 4 eyes (16. 67%) in TS group, but there were no statistically significant differences between two groups (P = 0. 068 > 0.05). Conclusion Long-term effects of non-penatrating trabecular surgery treating glaucoma were indefinite in some cases. It is very im-portant to choose the suitable surgery to gain high success rate.
Keywords:Trabecula  Micrurgy  Non-penetrating  Glaucoma
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