| 诱导成骨修复家兔桡骨缺损的实验研究 |
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| 引用本文： | 屠冠军 金耀清. 诱导成骨修复家兔桡骨缺损的实验研究[J]. 中国医科大学学报, 1997, 26(2): 153-155,158 |
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| 作者姓名： | 屠冠军 金耀清 |
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| 作者单位： | 第一临床学院骨科 |
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| 摘 要： | 定性、定量地了骨基质明胶和脱钙骨基质与自体红骨髓复合植入物修复家兔桡骨损的过程。结果表明两者均有诱导成骨作用，骨基质明胶的诱导成骨能力优于钙骨基质。术后６周，骨基质明胶组的骨缺损已完全愈合，而脱钙骨基质组接近愈合。作者认为含有骨形态发生蛋白的骨基持明胶和脱钙骨基质具有诱导成骨能力，而自体红骨髓为骨形态发生白提供诱导成骨的靶细胞。
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| 关 键 词： | 家兔 骨移植 诱导成骨 桡骨缺损 |
Induction of Osteogenesis in Repairing Bone Defects of Rabbits |
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| Tu Guanjun,Jin Yaoqing,Deng Xiangdong,et al. Induction of Osteogenesis in Repairing Bone Defects of Rabbits[J]. Journal of China Medical University, 1997, 26(2): 153-155,158 |
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| Authors: | Tu Guanjun Jin Yaoqing Deng Xiangdong et al |
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| Abstract: | The repairing of bone defects was conducted by composite grafts of bone matrix gelatin (BMG) and autogenous bone marrow (ABM) or demineralized bone matrix (DBM) and ABM respectively. We observed the process qualitatively and quantitatively. Both of them had the capacity of osteoinduction. BMG was superior to DBM. We concluded that BMG and DBM contained bone morphogenetic protein (BMP) which had the effect of osteoinduction, whereas ABM was the target cells of BMP. |
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| Keywords: | bone graft osteoinduction bone matrix gelatin mesenchymal cells |
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