| 红花黄素注射液细菌内毒素检测方法的实验研究 |
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| 引用本文： | 王著宇,李冬生,钱进.红花黄素注射液细菌内毒素检测方法的实验研究[J].中草药,2001,32(6):508-509. |
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| 作者姓名： | 王著宇 李冬生 钱进 |
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| 作者单位： | 1. 郑州化学药业有限公司,
2. 天津药物研究院, |
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| 摘 要： | 目的 建立测定红花黄素注射液细菌内毒素的方法。方法 通过进行红花黄素注射液的干扰试验考察，对30批红花黄素注射液进行了热源检查和细菌内毒素检查的对比试验。结果 红花黄素注射液对细菌内毒素检查法鲎试剂反应没有干扰作用，可以用鲎试剂法作内毒素检查。且本法的结果与家兔法检查热源的结果比较，符合率为100％。结论 方法简便、快速、准确。用本方法检测红花黄素注射液中的细菌内毒素是可行的。
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| 关 键 词： | 细菌内毒素试验 干扰试验 红花黄素注射液 |
| 文章编号： | 0253-2670(2001)06-0508-02 |
| 收稿时间： | 2000/11/27 0:00:00 |
| 修稿时间： | 2000年11月27 |
Experimental studies on bacterial endotoxin test of SAFFLOR INJECTION |
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| WANG Zhu yu,LI Dong sheng and QIAN Jin.Experimental studies on bacterial endotoxin test of SAFFLOR INJECTION[J].Chinese Traditional and Herbal Drugs,2001,32(6):508-509. |
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| Authors: | WANG Zhu yu LI Dong sheng and QIAN Jin |
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| Institution: | WANG Zhu yu 1,LI Dong sheng 1,QIAN Jin 2 |
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| Abstract: | Object To establish a method for the determination of bacterial endotoxin in SAFFLOR INJECTION * Methods Thirty batches of SAFFLOR INJECTION were subjected to Limulus lysate test in comparison with pyrogen test to ascertain whether there are any interference between the lysate and SAFFLOR INJECTION Results SAFFLOR INJECTION showed no inhibition or enhancement actions in bacterial endotoxin test with Limulus lysate, while showed a 100% coincidental rate with pyrogen test Conclusion This method was found to be simple, quick, accurate and is suitable for the determination of bacterial endotoxin in SAFFLOR INJECTION |
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| Keywords: | bacterial endotoxin test interfering test SAFFLOR INJECTION |
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