| 重组人生长激素治疗严重烧伤病人临床研究 |
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| 引用本文： | 杨新刚,李金娥,张宝泉,高伟,党正杰,王守峰.重组人生长激素治疗严重烧伤病人临床研究[J].中国冶金工业医学杂志,2008,25(5). |
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| 作者姓名： | 杨新刚 李金娥 张宝泉 高伟 党正杰 王守峰 |
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| 作者单位： | 1. 莱芜钢铁集团公司医院烧伤整形科 山东莱芜 271126
2. 莱芜钢铁集团公司医院特检科 山东莱芜 271126 |
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| 摘 要： | 目的:探讨生长激素对成人烧伤创面愈合时间、住院天数,用药前后白蛋白、BUN的变化,用药前后免疫蛋白含量变化。方法:选择2006年1月~2008年2月间30例严重烧伤患者为研究对象,并随机分为重组人生长激素组(r HG Hgroup)和对照组(control group),动态监测创面愈合时间、住院天数、蛋白、BUN、体重、免疫蛋白多项实验室指标。结果:创面愈合时间,住院天数,蛋白质的合成,提高烧伤后机体免疫力等r HGH组均优于对照组。结论:使用r HGH有助于改善全身状况,促进创面愈合,减少并发症。
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| 关 键 词： | 烧伤 重组人生长激素 创面愈合 |
The effect of recombinant human growth hormone in severe burned patients |
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| YANG Xin-gang,LI Jin-e,ZHANG Bao-quan,et al..The effect of recombinant human growth hormone in severe burned patients[J].Chinese Medical Journal of Metallurgical Industry,2008,25(5). |
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| Authors: | YANG Xin-gang LI Jin-e ZHANG Bao-quan |
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| Institution: | YANG Xin-gang,LI Jin-e,ZHANG Bao-quan,et al.Department of Burn,Laiwu Steel and Iron Hospital,Laiwu 271126 |
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| Abstract: | Objective:To determine the wound healing effect of rHGH in serious burned patients.Methods:30 patients from Jan 2006 to Feb 2008 with burn wounds were enrolled in this placebo controlled prospective study.Protein catabolism,immuncompetence,healing time of burn wounds,the length of hospital stay and donor sites were assayed.Results:The healing time of autologous skin pulp grafting and donor site,and the length of hospital stay were significantly shorter in GH group patients than control group.Conclusions:rHGH could enhance the wound healing rate,improve protein anabolism,and reduce the length of hospital stay of severe burned patients. |
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| Keywords: | Burn Recombinant human growth hormone Wound healing |
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