| 脂溢性皮炎样皮肌炎：一种特殊类型的皮肌炎 |
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| 引用本文： | 杨骥,徐欣植,李明.脂溢性皮炎样皮肌炎：一种特殊类型的皮肌炎[J].中华皮肤科杂志,2021,54(7):639-641. |
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| 作者姓名： | 杨骥 徐欣植 李明 |
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| 作者单位： | 复旦大学附属中山医院皮肤科，上海200032 |
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| 基金项目： | 国家自然科学基金（82073436）；上海市科技计划项目（20ZR1411500、19411962500）；上海市“医苑新星”青年医学人才培养资助计划；复旦大学“卓越2025”人才培育计划 |
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| 摘 要： | 【摘要】 介绍一种特殊类型的皮肌炎——脂溢性皮炎样皮肌炎，其特点为患者有面部脂溢性皮炎样皮疹，常伴有Gottron丘疹、反向Gottron丘疹、技工手和皮肤溃疡，很少累及肌肉。抗黑素瘤分化相关基因5抗体阳性的脂溢性皮炎样皮肌炎患者更易出现肺间质病变/急进性肺间质病变。通过皮疹联合抗体检测可对脂溢性皮炎样皮肌炎进行早期诊断，早期积极联合糖皮质激素和免疫抑制剂治疗可以提高患者的生存率。
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| 关 键 词： | 皮肌炎 脂溢性皮炎样皮肌炎 肺间质病变 |
| 收稿时间： | 2021-02-04 |
Seborrheic dermatitis-distributed dermatomyositis: a special type of dermatomyositis |
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| Yang Ji,Xu Xinzhi,Li Ming.Seborrheic dermatitis-distributed dermatomyositis: a special type of dermatomyositis[J].Chinese Journal of Dermatology,2021,54(7):639-641. |
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| Authors: | Yang Ji Xu Xinzhi Li Ming |
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| Institution: | Department of Dermatology, Zhongshan Hospital, Fudan University, Shanghai 200032, China |
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| Abstract: | 【Abstract】 Seborrheic dermatitis-distributed dermatomyositis, a special type of dermatomyositis, is characterized by facial seborrheic dermatitis-distributed rashes, usually accompanied by Gottron papules, inverse Gottron papules, mechanic′s hands and skin ulcers, seldom accompanied by muscle involvement. Anti-melanoma differentiation-associated gene 5 （MDA5） antibody-positive patients with seborrheic dermatitis-distributed dermatomyositis are prone to interstitial lung disease/rapidly progressive interstitial lung disease. Early diagnosis of seborrheic dermatitis-distributed dermatomyositis can be made through the combination of rashes and antibody detection, and early and active combined treatment with glucocorticoids and immunosuppressors can improve the survival rate of patients. |
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| Keywords: | Dermatomyositis Seborrheic dermatitis-distributed dermatomyositis Interstitial lung disease |
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