Microwave Ablation of Osteoid Osteomas Using Dynamic MR Imaging for Early Treatment Assessment: Preliminary Experience |
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Affiliation: | 1. Department of Radiology, Memorial Sloan–Kettering Cancer Center, 1275 York Ave., New York, NY 10065;2. San Diego Imaging, Sharp Memorial Hospital, San Diego, California;3. Department of Radiology, Centre Léon Bérard, Lyon, France;1. Department of Radiology, Division of Interventional Radiology, University of Colorado Denver, 12700 E. 19th Ave, Room P15-1205, Aurora, CO 80045;2. Department of Radiology, University of Colorado School of Medicine, Denver, Colorado;3. Department of Radiology, David Grant Medical Center, Travis AFB, California;4. Liver Transplantation Center, Baylor University Medical Center at Dallas, Dallas, Texas;1. Department of Obstetrics and Gynecology, Center for Integrated Oncology, University of Bonn, Sigmund-Freud-St 25, 53105 Bonn, Germany;2. Department of Radiology, Center for Integrated Oncology, University of Bonn, Bonn, Germany;1. Department of Diagnostic and Interventional Neuroradiology, Eberhard-Karls-University, Hoppe-Seyler-Str. 3, Tübingen 72076, Germany;2. University Eye Hospital, Department of Ophthalmology, Eberhard-Karls-University, Schleichstrasse 12, Tübingen 72076, Germany |
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Abstract: | PurposeTo evaluate the efficacy of microwave ablation for osteoid osteomas by using dynamic contrast-enhanced magnetic resonance (MR) imaging in early treatment assessment.Materials and MethodsTen patients (two female, eight male; mean age, 28 y; range, 16–47 y) presenting with osteoid osteomas were treated between June 2010 and December 2012 with the use of computed tomography (CT)–guided microwave ablation. Osteoid osteomas were found at the femoral neck (n = 4), tibia (n = 3), calcaneus (n = 1), navicular bone (n = 1), and dorsal rib (n = 1). Dynamic contrast-enhanced MR imaging at 3.0 T was performed 1 day before microwave ablation and again after ablation. The procedure was considered successful if the signal intensity (SI) of the lesion on MR imaging decreased by at least 50% and the patient was pain-free within 1 week of intervention.ResultsAll patients were pain-free within 1 week after microwave ablation and remained so during the 6 months of follow-up. No major or minor complications developed. On average, SI of the lesions decreased by 75% (range, 55.5%–89.1%) after treatment. The difference in lesion SI before versus after ablation was significant by t test (P < .0001; confidence interval, 120.26–174.96) and Wilcoxon test (P = .0020).ConclusionsMicrowave ablation treatment of osteoid osteoma was highly successful, without any complications observed. Dynamic contrast-enhanced MR imaging is a useful tool for diagnosing osteoid osteoma and evaluating treatment. |
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