| 神经梅毒研究现状及防治策略探索 |
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| 引用本文： | 王千秋,杜方智,张栩,张瑞丽.神经梅毒研究现状及防治策略探索[J].中华皮肤科杂志,2021,54(11):951-954. |
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| 作者姓名： | 王千秋 杜方智 张栩 张瑞丽 |
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| 作者单位： | 1中国医学科学院、北京协和医学院皮肤病研究所中国疾病预防控制中心性病控制中心临床防治室，南京210042；2南京医科大学第二附属医院皮肤科210015 |
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| 基金项目： | 国家自然科学基金;中国医学科学院医学与健康科技创新工程项目;南京市国家级临床医学中心培育计划项目 |
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| 摘 要： | 【摘要】 神经梅毒是梅毒最严重的临床类型之一。近年来我国文献报道的神经梅毒病例日益增多，但是其确切发病率不明，在神经梅毒的临床诊疗、发病机制和防控上仍存在一些关键科学问题亟需解决。因此本文提出CARE-NS策略，即在神经梅毒的多学科联合综合临床管理（C）、减轻神经系统损伤及预防后遗症的发生（A）、临床流行病学和危险因素研究（R）、病因学和发病机制研究（E）、新的诊断指标和诊断策略（N）、社会影响和成本效益分析（S）6个方面开展研究，为神经梅毒防治研究提供参考。
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| 关 键 词： | 神经梅毒 传染病控制 CARE-NS策略 |
| 收稿时间： | 2021-07-15 |
Neurosyphilis: current research status and management strategy exploration |
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| Wang Qianqiu,Du Fangzhi,Zhang Xu,Zhang Ruili.Neurosyphilis: current research status and management strategy exploration[J].Chinese Journal of Dermatology,2021,54(11):951-954. |
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| Authors: | Wang Qianqiu Du Fangzhi Zhang Xu Zhang Ruili |
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| Institution: | 1Institute of Dermatology, Chinese Academy of Medical Sciences and Peking Union Medical College/Department of Clinical Prevention and Control of STD, National Center for STD Control, Chinese Center for Disease Control and Prevention, Nanjing 210042, China; 2Department of Dermatology, The Second Affiliated Hospital of Nanjing Medical University, Nanjing 210015, China
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| Abstract: | 【Abstract】 Neurosyphilis is one of the most serious clinical manifestations of syphilis. In recent years, more and more neurosyphilis cases have been reported in Chinese literature. However, the exact incidence of neurosyphilis is unknown, and there are still some key scientific problems urgent to be solved in clinical diagnosis and treatment, pathogenesis, and prevention and control of neurosyphilis. Therefore, in order to provide a reference for the prevention and treatment of neurosyphilis, this article proposes the CARE-NS strategy, including the following 6 aspects: Comprehensive management including multiple disciplinary treatment（C）, Alleviating neurological impairment and sequelae （A）, Risk factors and clinical epidemiology （R）, Etiology and pathogenesis （E）, New diagnostic indicators and strategies （N）, Social impact and cost-effectiveness analysis （S）. |
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| Keywords: | Neurosyphilis Communicable disease control CARE-NS strategy |
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