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Nonalcoholic fatty liver disease and bariatric surgery in adolescents |
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| Affiliation: | 1. Department of Internal Medicine, Chosun University School of Medicine, Gwangju 501-759, Republic of Korea;2. Department of Biomaterials, Chosun University Graduate School, Gwangju 501-759, Republic of Korea;3. Department of Biochemistry and Molecular Biology, Chosun University School of Medicine, Gwangju 501-759, Republic of Korea |
| Abstract: | Obesity is a multi-organ system disease with underlying insulin resistance and systemic chronic inflammation. Nonalcoholic fatty liver disease (NAFLD) is a hepatic manifestation of the underlying metabolic dysfunction. This review provides a highlight of the current understanding of NAFLD pathogenesis and disease characteristics, with updates on the challenges of NAFLD management in obese and severely obese (SO) patients and recommendations for the pediatric surgeons' role in the care of SO adolescents. |
| Keywords: | Nonalcoholic fatty liver disease Metabolic dysfunction Adolescent morbid obesity |
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