| 免疫检查点抑制剂所致皮肤免疫相关不良反应的研究进展 |
| |
| 引用本文： | 邹美熔 汪盛. 免疫检查点抑制剂所致皮肤免疫相关不良反应的研究进展[J]. 中华皮肤科杂志, 2022, 55(11): 1026-1030. DOI: 10.35541/cjd.20201221 |
| |
| 作者姓名： | 邹美熔 汪盛 |
| |
| 作者单位： | 四川大学华西医院皮肤科，成都610041 |
| |
| 摘 要： | 【摘要】 作为一类新型的抗癌药物，免疫检查点抑制剂在被广泛应用于多种肿瘤治疗的同时，也导致许多免疫相关不良反应，其中以皮肤相关不良反应最为常见。皮肤免疫相关不良反应发病早、大多数程度较轻，但也会出现危及生命的情况。本文综述免疫检查点抑制剂所致皮肤免疫相关不良反应的研究进展。
|
| 关 键 词： | 药物毒性 CTLA-4抗原 程序性细胞死亡受体1 皮肤表现 免疫检查点抑制剂 |
| 收稿时间： | 2020-12-24 |
Cutaneous immune-related adverse reactions induced by immune checkpoint inhibitors |
| |
| Zou Meirong,Wang Sheng. Cutaneous immune-related adverse reactions induced by immune checkpoint inhibitors[J]. Chinese Journal of Dermatology, 2022, 55(11): 1026-1030. DOI: 10.35541/cjd.20201221 |
| |
| Authors: | Zou Meirong Wang Sheng |
| |
| Affiliation: | Department of Dermatology, West China Hospital, Sichuan University, Chengdu 610041, China
|
| |
| Abstract: | 【Abstract】 As a new type of anti-cancer drugs, immune checkpoint inhibitors have been widely used for the treatment of various tumors in recent years, but they have also caused a variety of immune-related adverse reactions, among which cutaneous adverse reactions are the most common. The onset of cutaneous adverse reactions was usually early, and most are mild, but some can also be life-threatening. This review summarizes recent advances in cutaneous immune-related adverse reactions induced by immune checkpoint inhibitors. |
| |
| Keywords: | Drug toxicity CTLA-4 antigen Programmed cell death 1 receptor Skin manifestations Immune checkpoint inhibitors |
|
| 点击此处可从《中华皮肤科杂志》浏览原始摘要信息 |
|
点击此处可从《中华皮肤科杂志》下载全文 |
