| 非大疱性类天疱疮 |
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| 引用本文： | 闪莹,常晓彤,左亚刚.非大疱性类天疱疮[J].中华皮肤科杂志,2022,55(10):922-924. |
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| 作者姓名： | 闪莹 常晓彤 左亚刚 |
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| 作者单位： | 1中国医学科学院、北京协和医学院北京协和医院皮肤科协和医学转化中心国家皮肤与免疫疾病临床医学研究中心，北京100730；2河北北方学院，张家口075000 |
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| 基金项目： | 国家自然科学基金（81972944）；北京市自然科学基金（7192166） |
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| 摘 要： | 【摘要】 非大疱性类天疱疮与大疱性类天疱疮相关，临床表现多样，多数伴有瘙痒，缺乏大疱性类天疱疮的紧张性水疱或大疱的典型临床表现，误诊率高。组织病理缺乏特异性，需要依靠直接免疫荧光、间接免疫荧光或盐裂间接免疫荧光明确诊断。部分无疱性类天疱疮会发展为大疱性类天疱疮，预后较大疱性类天疱疮好，但由于易被延迟诊断，使得控制症状的药物用量大，药物不良反应多。
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| 关 键 词： | 类天疱疮 大疱性 荧光抗体技术 非大疱性类天疱疮 前驱性大疱性类天疱疮 |
| 收稿时间： | 2020-05-20 |
Nonbullous pemphigoid |
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| Shan Ying,Chang Xiaotong,Zuo Yagang.Nonbullous pemphigoid[J].Chinese Journal of Dermatology,2022,55(10):922-924. |
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| Authors: | Shan Ying Chang Xiaotong Zuo Yagang |
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| Institution: | 1Department of Dermatology, National Clinical Research Center for Skin and Immune Diseases, Translational Medicine Center of Peking Union Medical College Hospital, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100730, China; 2Hebei North University, Zhangjiakou 075000, Hebei, China |
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| Abstract: | 【Abstract】 Nonbullous pemphigoid （NBP）, which is related to bullous pemphigoid, has various clinical manifestations, and is frequently accompanied by itching. Typical clinical manifestations of bullous pemphigoid （BP）, such as tense blisters or bullae, are absent in NBP cases. It is easy to misdiagnose. Histopathological findings are not specific, so diagnosis should be confirmed by direct immunofluorescence, indirect immunofluorescence or salt-split indirect immunofluorescence. NBP may develop into BP in some cases, and the prognosis of NBP is better than that of BP. However, delayed diagnosis usually leads to a relatively high dosage of drugs for disease control, and a high rate of adverse reactions. |
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| Keywords: | Pemphigoid bullous Fluorescent antibody technique Nonbullous pemphigoid Prodromal pemphigoid |
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