中药卫骨胶囊治疗骨质疏松症的临床观察

目的：观察应用中药卫骨胶囊治疗原发性骨质疏松症的临床效果。方法：骨密度值低于同一性别1个标准差，没有合并症，未经过治疗的骨量减少及骨质疏松症患作为观察对象，共25例，另选30例患作为对照组，在治疗组25例中男性4例，女性21例；对照组30例中，男性8例，女性22例，治疗组用卫骨胶囊，每日3次，每次4粒，服药6个月后复查，对照组用维生素D1000IU加钙片1g，每日3次，服药6个月后复查，观察指标中医辨证按临床设计方案，于用药前、用药6个月后各记录1次；骨密度测定，应用双能X线测腰椎2－4的骨密度，用药前后各测定一次。结果：（1）卫骨胶囊总有效率为96％，明显优于对照组，经统计学处理，差异非常显，P＜0．01，其中显效率为88％；（2）服用卫骨胶囊后，骨密度值上升变化差异显，P＜0．01，（3）卫骨胶囊对骨质疏松所兼的中医证肾虚气血不足治疗总有效率为96％，而对照组为205，两组对比差异非常显，P＜0．01。结论：中药卫骨胶囊具有治疗骨质疏松症的功效。

Clinical trail of Traditional Chinese Medicine Wei Gu Capsule on the therapy of osteoporosis

Objective To observe the clinical effect of Traditional Chinese Medicine(TCM)Wei Gu Capsule on the therapy of osteoporosis. Methods We choose 55 patients with osteopenia or osteoporosis whose bone mineral density(BMD)decreased more than one standard deviation and no complications were accompanied,including 25 patients treated with Wei Gu Capsule and 30 patients as control.Wei Gu Capsule should be taken three times per day,four capsules per time in the treatment group.Vitamin D 1000IU and calcium 1.0 gram should be taken three times per day in the control group.The patients came back to the hospital for a check ater 6 months.The overall analysis of TCM based on symptoms and signs according to the clinical design were recorded and BMD at the 2 nd to 4th lumber vertebrae measured by double X ray scanning were examined before and after 6 months treatment,respectively. Results (1)The total efficacious rate of Wei Gu is 96 percent,which is significant better than the control.The statistical analysis show a significant difference, P <0 01.Among them marked efficiency rate is 88 percent;(2)The BMD of the treatment group increased significantly compared with that of the control group, P <0 001;(3)The total efficacious rate of Wei Gu treating the deficiency of Qi and Xue in TCM is 96 percent,while only 20 percent in the control group.The difference is signficant, P <0 001. Conclusion The TCM Wei Gu Capsule is effective on the therapy of osteoporosis.;