胶体治疗在门脉高压症患者门奇断流术后的应用分析

目的探讨胶体治疗在乙肝肝硬化门脉高压症患者脾切除门奇断流术后应用的安全性和有效性。方法选择2009年1月~2013年12月在本院普外科住院,接受脾切除门奇静脉断流的乙肝肝硬化门脉高压症患者159例,随机分为治疗组87例及对照组72例。对照组采用传统的围术期治疗方法,治疗组额外采用0.6%羟乙基淀粉130/0.4氯化钠500 ml/d常规输注;采集不同组间患者围手术期并发症发生、住院时间、输液总量、白蛋白及血浆输入总量、首次排气及排便时间、低蛋白血症纠正时间、住院经费等指标,统计分析两组间术后并发症发生及相关指标差异,以评估羟乙基淀粉在乙肝肝硬化门脉高压症患者脾切除门奇断流术围手术期诊疗中应用的安全性和有效性。结果治疗组切口并发症、胃肠道功能障碍、水电解质平衡紊乱、胸腹水及总计并发症发生均较低,较对照组差异显著,有统计学意义(P0.05)。与对照组比较,治疗组白蛋白输注量、补液总量及住院费用显著减少,出入院体重下降值增加,差异具有统计学意义(P0.05)。结论在乙肝肝硬化门脉高压症患者脾切除门奇断流术后实施胶体治疗是安全、有效的,可减少术后并发症出现、降低白蛋白输注总量及住院费用,对患者术后治疗具有积极意义。

Application Analysis of Colloid Therapy after Operation on Patients undergoing Pericardial Devascularization with Portal Hypertension

Objective To investigate the safety of Colloid Therapy after Operation on patients undergoing Pericardial devascu- larization with Portal hypertension. Methods 159 patients with Portal hypertension from Jan 2009 to Dec 2013 were divided into the treatment group （ n = 87 ） and the control group （ n =72）. The treatment group recept the Colloid Therapy, while the control group was given the routine curing. Timely collection of the related indicators of efficacy and safety performed well. Results Treatment group of patients with incision complications, gastrointestinal dysfunction, water electrolyte balance disorders, hydrothorax, ascites and total complications were lower than the control group, significant difference was statistically significant （P 〈 0. 05）. Compared with the con- trol group, postoperative albumin, the total infusion and hospitalization expenses of the treatment group were significantly reduced, while the Weight loss was significantly increased, the difference was statistically significant （P 〈 0. 05）. Conclusion The application of Colloid Therapy is safe and effective in postoperative therapy of Patients with Portal hypertension, and it can significantly promote the rehabilitation, reduce the postoperative complications, lower the albnmin usage and hospitalization expenses, and has positive significance for the postoperative treatment for the patients.