| 动脉瘤性蛛网膜下腔出血的反思 |
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| 引用本文： | 冯华,唐卫华. 动脉瘤性蛛网膜下腔出血的反思[J]. 解放军医学杂志, 2011, 36(12): 1259-1262 |
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| 作者姓名： | 冯华 唐卫华 |
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| 作者单位： | 全军神经系统疾病微创诊治专科中心、全军神经创伤防治重点实验室, 重庆 第三军医大学西南医院神经外科,400038 |
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| 基金项目： | 国家自然科学基金(30973101,30772224,30801186,30900466); 重庆市国际合作重大项目(2011GZ0040) |
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| 摘 要： | 颅内动脉瘤本身是一种良性疾病,但其伴发的动脉瘤性蛛网膜下腔出血(aSAH)却严重制约了临床疗效.前期的研究显示脑内大动脉痉挛是导致临床预后不良的关键因素,但近来内皮素A受体拮抗剂的临床实验结果却显示脑内大血管痉挛可能并非关键因素.aSAH的研究重点也因此转向了以微循环障碍、皮质播散性抑制、早期脑损害、血-脑脊液屏障损伤...
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| 关 键 词： | 颅内动脉瘤 蛛网膜下腔出血 神经外科手术 |
Introspection to aneurysmal subarachnoid hemorrhage |
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| FENG Hua , TANG Wei-hua. Introspection to aneurysmal subarachnoid hemorrhage[J]. Medical Journal of Chinese People's Liberation Army, 2011, 36(12): 1259-1262 |
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| Authors: | FENG Hua TANG Wei-hua |
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| Affiliation: | FENG Hua,TANG Wei-hua.Department of Neurosurgery,Southwest Hospital,Third Military Medical University,Chongqing,400038,China |
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| Abstract: | Intracranial aneurysm itself is a benign disease,but its associated aSAH restricted clinical outcomes seriously.Previous studies have shown that lager cerebral artery spasm is the key factor that leads to poor clinical prognosis.However,recent clinical trial of endothelin A receptor antagonist have shown a different result.Thus,aSAH research has shifted to some new focus,such as microcirculation dysfunction,cortical spreading depolarization,early brain injury,blood-cerebrospinal fluid barrier damage,and inf... |
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| Keywords: | intracranial aneurysm subarachnoid hemorrhage neurosurgical procedures |
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