| 格林-巴利综合征患者脑脊液抗P2蛋白IgG抗体增高 |
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| 引用本文： | 邓国民,林嘉友,许贤豪,杜彦辉,魏岗之. 格林-巴利综合征患者脑脊液抗P2蛋白IgG抗体增高[J]. 中国神经免疫学和神经病学杂志, 1994, 1(2): 98-102 |
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| 作者姓名： | 邓国民 林嘉友 许贤豪 杜彦辉 魏岗之 |
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| 作者单位： | 中国医学科学院协和医院神经科，中国医学科学院基础医学研究所免疫研究室，宁夏医学院神经内科，首都医科大学宣武医院神经内科 |
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| 摘 要： | 用ＥＬＩＳＡ方法，检测３６例格林－巴利综合征（ＧＢＳ）患者和４０例其他神经病（ＯＮＤ）患者的血清和脑脊液及４０例健康对照（ＮＣ）血清标本的抗Ｐ２蛋白ＩｇＧ和ＩｇＭ抗体。结果发现：ＧＢＳ和ＯＮＤ血清抗Ｐ２Ｉｇ６和ＩｇＭ抗体与ＮＣ血清比较无明显差异（Ｐ＞０．０５）。ＧＢＳ脑脊液抗Ｐ２ＩｇＧ抗体明显高于ＯＮＤ（Ｐ＜０．０５），而抗Ｐ２ＩｇＭ抗体则两者无显著差异（Ｐ＞０．０５）。
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| 关 键 词： | 脑脊液 IgG抗体 IgM抗体 GBS 患者 格林-巴利综合征 蛋白 发现 |
Anti-P2 Protein IgG Antibody in CSF of Patients with GBS |
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| Deng Guomin, Lin Jiayou, Xu Xianhao,Du Yanhui, Wei Gangzhi. Anti-P2 Protein IgG Antibody in CSF of Patients with GBS[J]. Chinese Journal of Neuroimmunology and Neurology, 1994, 1(2): 98-102 |
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| Authors: | Deng Guomin Lin Jiayou Xu Xianhao Du Yanhui Wei Gangzhi |
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| Abstract: | IgG and IgM antibodies against P2 protein were measured by ELISA in serum and cerebrospinal fluid of 36 patients with GBS,40 patients with OND,and in serum of 32 NC.There were no significantly increased IgG and IgM antibodies to P2 protein in sera of patients with GBS.IgG antibody to P2 protein in cerebrospinal fluid was significantly higher in patients with GBS than that in OND(P<0.05),but IgM antibody was not(P>0.05). |
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| Keywords: | Guillain-Barre syndrome P2 protein antibody ELISA |
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