舒芬太尼联合丙泊酚静脉麻醉在腹腔镜胆囊切除术中的麻醉作用研究

目的 探讨舒芬太尼联合丙泊酚静脉麻醉在腹腔镜胆囊切除术中的麻醉效果。方法 选取182例须行腹腔镜胆囊切除术患者，随机分为两组，对照组（81例）给予瑞芬太尼联合丙泊酚静脉麻醉，观察组（101例）给予舒芬太尼联合丙泊酚静脉麻醉。观察并记录两组患者术后自主呼吸恢复时间、睁眼时间、拔管时间，术后1、6、12 h的VAS评分及麻醉期间患者并发症情况，评价舒芬太尼复合丙泊酚静脉麻醉在腹腔镜胆囊切除术中的麻醉效果。结果 观察组自主呼吸恢复时间、睁眼时间、拔管时间均明显长于对照组（P<0.05）；术后1、6、12 h，观察组患者VAS评分明显低于对照组（P<0.05）；麻醉期间，观察组患者出现苏醒期躁动的比例明显低于对照组，并发症总发生率也明显低于对照组（P<0.05）。结论 舒芬太尼联合丙泊酚对腹腔镜胆囊切除术后患者具有良好的麻醉作用，患者术后痛觉感受轻微，少苏醒期躁动，值得临床推广使用。

Clinical efficacy of Sufentanil combined with propofol in intravenous anesthesia during laparoscopic cholecystectomy

Objective To discuss the efficacy of sufentanil combined with propofol in iv anesthesia during laparoscopic cholecystectomy.Methods Totally 182 patients received laparoscopic cholecystectomy. They were divided into two groups according to odd or even number of hospitalization. The control group (81 cases) were given remifentani combined with propofol for iv anesthesia. The observation group (101 cases) were given sufentanil combined with propofol for iv anesthesia. The anesthetic effect of sufentanil combined with propofol for iv anesthesia during laparoscopic cholecystectomy was evaluated by breathing recovery time, opening time, extubation time, VAS scores after 1, 6, 12 h, and complications during anesthesia.Results Breathing recovery time, opening time, and extubation time of observation group were longer than those of control group (P<0.05). The VAS scores after 1, 6, and 12 h of observation group were lower than those of the control group (P<0.05). During anesthesia, the proportion of restlessness in observation group was lower than that in control group (P<0.05). The complication rate of observation group was lower than that of control group (P<0.05).Conclusion Sufentani combined with propofol has a good anesthetic effect on patients receiving laparoscopic cholecystectomy with mild postoperative pain and less restlessness. It is worthy of clinical use.