复方樟柳碱联合卵磷脂络合碘片对中心性浆液性脉络膜视网膜病变的临床观察

目的 探讨复方樟柳碱联合卵磷脂络合碘片对中心性浆液性脉络膜视网膜病变的疗效。方法 选取60例中心性浆液性脉络膜视网膜病变患者，按随机数字表法分为两组，对照组（29例）口服卵磷脂络合碘片1.5 mg/次，3次/d；观察组在对照组基础上静脉推注复方樟柳碱注射液2 mL，1次/d，两组均治疗14 d。观察并记录两组疗效，视力水平，光敏感度及治疗期间不良反应，评价复方樟柳碱联合卵磷脂络合碘片治疗中心性浆液性脉络膜视网膜病变的疗效。结果 治疗后，观察组患者治疗有效率为93.5%，对照组患者治疗有效率为79.3%，观察组有效率明显高于对照组（P<0.05）；治疗前两组视力水平无统计学差异，治疗后两组时间视力水平均明显提高且观察组视力更好（P<0.05）；治疗前，两组光敏感度无统计学差异，治疗后2、4周，两组光敏感度均明显提高，且观察组光敏感度值更高（P<0.05）。治疗期间，两组不良反应率无统计学差异。结论 复方樟柳碱联合卵磷脂络合碘片对中心性浆液脉络膜视网膜病变具有较好疗效，能够提高患者视力，改善眼部光敏感度，用药具有安全性，值得临床推广使用。

Clinical analysis of Compound Anisodine Injection combined with Iodized Lecithin Tablets in treatment of central serous chorioretinopathy

Objective To discuss the efficacy of Compound Anisodine Injection combined with Iodized Lecithin Tablets in treatment of central serous chorioretinopathy.Methods Totally 60 patients with CSC were selected, and divided into two groups randomly. The patients in control group (29 cases) were given Iodized Lecithin Tablets. The patients in observation group (31 cases) were given Iodized Lecithin Tablets and Compound Anisodine Injection. The efficacy of Compound Anisodine Injection combined with Iodized Lecithin Tablets in treatment of central serous chorioretinopathy was evaluated by efficacy, visual acuity, light sensitivity, and adverse reaction during treatment.Results After treatment, the effective rates of observation and control groups were 93.5% and 79.3%, and the observation group was significantly higher than control group (P<0.05). There were no statistical significance on visual acuity between two groups. After treatment, rhe visual acuity of two groups was increased and the visual acuity in the observation group was better (P<0.05). Before treatment, there were no statistical significance on light sensitivity between two groups. After 2 and 4 weeks treatment, the light sensitivity of two groups were increased and the light sensitivity in the observation group was higher (P<0.05). During treatment, there was no statistical significance on adverse reaction between two groups.Conclusion Compound Anisodine Injection combined with Iodized Lecithin Tablets has a curative effect on central serous chorioretinopathy. It could increase the visual acuity and improve the light sensitivity of eyes with good security. It is worthy of clinical use.