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| 利用药用真菌深层发酵加工中药 | |
| 引用本文： | 杨海龙,陈高洪,章克昌. 利用药用真菌深层发酵加工中药[J]. 中国中药杂志, 2005, 30(21): 1717-1720 |
| 作者姓名： | 杨海龙 陈高洪 章克昌 |
| 作者单位： | 1. 温州大学,生命与环境科学学院,浙江,温州,325027 2. 浙江医药股份有限公司,浙江,绍兴,312000 3. 江南大学生物工程学院,江苏,无锡,214036 |
| 摘 要： | 加工技术陈旧是中药现代化进展缓慢原因之一。药用真菌的深层发酵技术日趋成熟,利用它们的分解转化能力对中药进行发酵加工,可以提高中药中活性成分的单位浓度;同时药用真菌亦会产生丰富多样的活性次生代谢产物,而且药用真菌还可对中药中的某些成分进行转化形成新的化合物。利用药用真菌发酵中药可开发包含多种活性成分的新型中药制剂,有利于大规模生产及质量控制。利用药用真菌深层发酵加工中药为中药的加工开辟了新的手段。 |
| 关 键 词： | 药用真菌 发酵加工 中药 |
| 文章编号： | 1001-5302（2005）21-1717-04 |
| 收稿时间： | 2004-10-27 |
| 修稿时间： | 2004-10-27 |
The process of Chinese medicine by submerged fermentation of pharmaceutical fungi |
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| YANG Hai-long;CHEN Gao-hong;ZHANG Ke-chang. The process of Chinese medicine by submerged fermentation of pharmaceutical fungi[J]. China Journal of Chinese Materia Medica, 2005, 30(21): 1717-1720 | |
| Authors: | YANG Hai-long CHEN Gao-hong ZHANG Ke-chang |
| Affiliation: | School of biological & environmental sciences, Wenzhou university, Wenzhou 325027, China. yhl@wznc.zj.cn |
| Abstract: | The progress of Chinese medicine modernization is slow in china,and one of the reason is the dated process method.The fermentation technology of pharmaceutical fungi is more and more perfect.To process Chinese medicine by pharmaceutical fungi could enhance the effective density of active ingredient in Chinese medicine,and the fungi could produce a variety of active secondary metabolite,moreover,some compounds in Chinese medicine could be bio-transformed to produce new compound by pharmaceutical fungi in the fermentation.So process Chinese medicine by pharmaceutical fungi could produce de novo Chinese medicine preparations which include a variety of bioactive compounds,and it is suitable to produce in a large scale and convenient to control the quality.To process Chinese medicine by submerged fermentation of pharmaceutical fungi provides a new process method for Chinese medicine. |
| Keywords: | pharmaceutical fungi fermentation process Chinese medicine |
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