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Low Thymic Output,Peripheral Homeostasis Deregulation,and Hastened Regulatory T Cells Differentiation in Children with 22q11.2 Deletion Syndrome |
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| Authors: | Sara Ferrando-Martínez PhD Raquel LorenteDolores Gurbindo MD PhD M Isabel De José Manuel Leal M Angeles Muñoz-Fernández Rafael Correa-Rocha |
| Institution: | 1 Laboratory of Molecular Immunobiology, Instituto de Investigación Sanitaria Gregorio Marañón (IISGM), Madrid, Spain;2 Laboratorio de Inmunovirología, Instituto de Biomedicina de Sevilla (IBIS), Unidad clínica de Enfermedades Infecciosas, Microbiología y Medicina Preventiva, Hospital Virgen del Rocío, Universidad de Sevilla, Sevilla, Spain;3 Sección de Inmunopediatría, Hospital General Universitario Gregorio Marañón, Madrid, Spain;4 Servicio de Enfermedades Infecciosas Infantil, Hospital Universitario “La Paz”, Madrid, Spain;5 Networking Research Center on Bioengineering, Biomaterials and Nanomedicine (CIBER-BBN), Madrid, Spain |
| Abstract: | |
| Keywords: | β-TREC DβJβ-T&minus cell receptor excision circle IL Interleukin IL-7Rα IL-7-receptor chain α PBMC Peripheral blood mononuclear cell PCR Polymerase chain reaction sj/β-TREC Signal-joint/DβJβ-T cell receptor excision circle sj-TREC Signal-joint T-cell receptor excision circles Treg Regulatory T cells |
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